Results 191 to 200 of about 5,617,123 (302)

Using inclusive fitness and eco-evolutionary theory to model cultural evolution. [PDF]

Evol Hum Behav
Iritani R, West SA.
europepmc   +1 more source

Neighbours and relatives: accounting for spatial distribution when testing causal hypotheses in cultural evolution. [PDF]

Evol Hum Sci, 2023
Bromham L, Yaxley KJ.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Contrasting modes of cultural evolution: Kra-Dai languages and weaving technologies. [PDF]

Evol Hum Sci
Buckley CD, Kopp E, Pellard T, Ryder RJ, Jacques G.   +4 more
europepmc   +1 more source

Context congruence: How associative learning modulates cultural evolution. [PDF]

PLoS One, 2023
Tamariz M, Papa A, Cristea M, McGuigan N.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Context, Consequence, Coincidence, and Cumulative Cultural Evolution: Linking Creativity and Culturo-Behavioral Phenomena Together Using Systems Principles and Processes of Selection by Consequences. [PDF]

Perspect Behav Sci
Krispin JV.
europepmc   +1 more source

Generative cultural learning in children and adults: the role of compositionality and generativity in cultural evolution. [PDF]

Proc Biol Sci, 2023
Varallyay A, Beller N, Subiaul F.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Author Correction: The evolutionary dynamics of how languages signal who does what to whom

Scientific Reports
Olena Shcherbakova, Damián E. Blasi, Volker Gast, Hedvig Skirgård, Russell D. Gray, Simon J. Greenhill   +5 more
doaj   +1 more source