Results 121 to 130 of about 380,636 (306)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Narrative, Identity, and the Map of Cultural Policy Once upon a Time in a Globalized World

open access: yes
The story of arts and cultural policy in the twenty-first century is inherently of global concern no matter how local it seems. At the same time, questions of identity have in many ways become more challenging than before.
DeVereaux, Constance., Griffin, Martin.
core  

Mind in Africa, Body in Europe: The Struggle for Maintaining and Transforming Cultural Identity - A Note from the Experience of Eritrean Immigrants in Stockholm [PDF]

open access: yes
This paper describes how individuals and groups who had crossed ‘physical, national boundaries’, and who live in a different social context make sense of their lives make sense of their lives by re-constructing their identities - of the sense of who they
Kiflemariam Hamde
core  

Identity Development in Adulthood : Introduction

open access: yes, 2016
In line with Erikson’s suggestions, increasing empirical evidence substantiates that considerable identity development takes place over the course of adulthood. What then does identity development during adulthood entail?
Kroger, Jane, Fadjukoff, Päivi
core   +1 more source

How cutting- edge technologies shape cultural identity in ultramodern Arabic literature

open access: yesSocial Sciences and Humanities Open
The research aimed to delve into the complex relationship between technology and cultural identity in Arabic literature, examining both the positive and negative aspects of this relationship.
Mohammad Saleh Bani Issa
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Cultural identity and academic achievement among Māori undergraduate university students

open access: yes, 2003
Cultural identity and academic achievement were investigated among a nonrandom sample of 72 undergraduate Māori university students studying at Massey University.
Bennett, Simon T.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Evaluating the psychometric properties of the multigroup ethnic identity measure (MEIM) within the United Kingdom

open access: yes, 2010
In the present study, we examined the psychometric properties of the Multigroup Ethnic Identity Measure (MEIM) (Phinney, 1992; Phinney & Alipuria, 1990) among an ethnically diverse sample within the United Kingdom.
Wright, B   +3 more
core   +1 more source

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