Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Bridging cultural binaries through pedagogical practices [PDF]
, 2013 In internationalising the curriculum, the move away from polarising domestic and international students to focus on preparing all students for global citizenship is promising.
Meerwald, A.M.L.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
How cutting- edge technologies shape cultural identity in ultramodern Arabic literature
Social Sciences and Humanities OpenThe research aimed to delve into the complex relationship between technology and cultural identity in Arabic literature, examining both the positive and negative aspects of this relationship.
Mohammad Saleh Bani Issa
doaj +1 more source
Social representations of national identity in culturally diverse societies [PDF]
, 2015 The concept of identity, although quite recent in the social sciences (it was popularized by Erikson in the 1950s; see Gleason, 1983), is one of the few concepts to have been so widely studies and theorized. Psychologists, sociologists, anthropologists,
Andreouli, Eleni, Chryssochoou, Xenia
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Dynamic Notion of Cultural Identity: Implications for Human Rights [PDF]
, 2012 Post Modern Cultural Identity and Human Rights. Theoretical Traditions in Cultural Identity. The Dynamic Notion of Cultural Identity: A Reversion to the Essentialist Paradigm.
Pande, Dhruv
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Cross-cultural management and bicultural identity integration: When does experience abroad lead to appropriate cultural switching? [PDF]
, 2011 Ray Friedman +4 more
openalex +1 more source
Indeliable exhibition: Yellow river boat (2018): Trap (2018) [PDF]
, 2018 This exhibition is one of two that make up a cultural and artistic exchange project with Xi'an Art Museum, Xi'an City, Shaanxi Province, China; Waikato Museum, Hamilton, NZ; and Wintec researchers (Hamilton, NZ).
Williams, Gareth C. A.
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