Results 71 to 80 of about 2,058,141 (351)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cultural identity and right to education
The central theme of the article is the presentation of the arguments in favor of the right to cultural identity and the discussion about its limits. It aims to show the problem involved in the claim of differentiated identity in education and explore ...
Juan Manuel Fernández Soria
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
International Trade and Cultural Identity [PDF]
Economists emphasize the benefits from free trade due to international specialization, but typically have a narrow measure of what matters to individuals.
Eckhard Janeba
core
Introduction To Latinx Literature And Culture (SPAN015 / LITR 15S) Syllabus [PDF]
This First Year Seminar is an introduction to the writings of Latino/as in the U.S. with emphasis on the distinctions and similarities that have shaped the experiences and the cultural imagination among different Latinx communities.
Diaz, Désirée
core +2 more sources
When does group norm or group identity predict cooperation in a public goods dilemma? The moderating effects of idiocentrism and allocentrism [PDF]
In this study we examined how perceived group norm and group identity influence individual cooperative behavior in a public goods dilemma across cultural settings.
Chen, Xiao-Ping +2 more
core +1 more source

