Results 51 to 60 of about 779,176 (289)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

What Makes Theatrical Performances Successful in China's Tourism Industry? [PDF]

, 2012
This study aims to explore the factors affecting the success of a popular tourist product, namely, theatrical performance, within the context of China's tourism industry and develop a model based on previously successful productions.
Catherine Cheung, d'Hauteserre A. M., Daniel Y. P., Dou Q., Edhlund B. M., Glesne C., Hanqun Song, Henard D. H., Hsu C. H. C., Li C., Loi K. I., McDaniel C., Morrison A. M., Pearce P. L., Pearce P. L., Qiao G., Reid R. D., Rong H., Ryan C., Song H., Song H., Swarbrooke J., Tian M., Wang C., Wei X., Zeithaml V. A., Zhang H. Q., Zhuge Y.   +27 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

From cultural industries to creative economy: The popular culture within the public policy [PDF]

TIMS: Acta, 2014
Lately, creative industries have become an extremely popular concept in cultural policies across the globe. For many, it came as a surprise. However, the idea of merging culture and arts with industrial production has been slowly evolving during the 20th
Tomka Goran
doaj   +1 more source

Soft power, global governance of cultural industries and rising powers: the case of China [PDF]

, 2016
This article addresses the importance of cultural industries for the strengthening of the soft power of the rising powers and it seeks to understand how the cultural industries allow rising powers to shape the structures of their international ...
Vlassis, Antonios
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Moebius strip enterprises and expertise in the creative industries: new challenges for lifelong learning? [PDF]

, 2007
The paper argues that the emergence of a new mode of production – co-configuration is generating new modes of expertise that EU policies for lifelong learning are not designed to support professionals to develop. It maintains that this change can be seen
Beynon H., Billett S., Boden M., Bourdieu P., Bourdieu P., Brandom R., Coffe D., Csikszentmihalyi M., David Guile, Engeström Y., Engeström Y., Engeström Y., Florida R., Frith S., Gardner H., Ghosal S., Ghoshal S., Griffiths T., Guile D., Guile D., Howkins J., Kaufman J., Knorr Cetina K., Lave J., Nonaka I., Piore M., Sabel C., Sternberg R., Unwin L., Victor B., Warmington P., Wood S.   +31 more
core   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Literature Review of the Definition, Size and Turnover of the Creative Industries and Micro-Businesses in Scotland: Preliminary Research [PDF]

, 2013
This research seeks to review, evaluate and clarify the findings of five recent reports in relation to the discussion paper Creative Industries in Scotland.
Sorensen, Inge
core