Results 71 to 80 of about 783,916 (309)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Social network market: Storytelling on a web 2.0 original literature site [PDF]

open access: yes, 2011
This article looks at a Chinese Web 2.0 original literature site, Qidian, in order to show the coevolution of market and non-market initiatives. The analytic framework of social network markets (Potts et al., 2008) is employed to analyse the motivations ...
Anderson C.   +38 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

CULTURAL-PRODUCTS INDUSTRIES AND URBAN ECONOMIC DEVELOPMENT: PROSPECTS FOR GROWTH AND MARKET CONTESTATION IN GLOBAL CONTEXT [PDF]

open access: yes
The paper opens with a brief definition of the cultural economy. A first generation of local economic development policy approaches based on place-marketing and associated initiatives is described.
Allen J Scott
core  

Are workers in the cultural industries paid differently? [PDF]

open access: yes, 2007
This paper aims to explore wage differentials between employees in three sub-industries of the cultural industries compared with the main (1-digit level) industry to which they belong.
Wetzels, Cecile
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Why do creative industries cluster? An analysis of the determinants of clustering of creative industries [PDF]

open access: yes
Creative industries tend to concentrate mainly around large- and medium-sized cities, forming creative local production systems. The text analyses the forces behind clustering of creative industries to provide the first empirical explanation of the ...
Francesco Capone   +2 more
core  

A Commentary on Taiwan’s Creative and Cultural Industries [PDF]

open access: yes, 2017
. A commentary is offered for the further development of Taiwanese cultural and creative industries (CCI). Although there have been some scant successful cases in the context, more systematic and value co-creating efforts should be committed.
HUANG, Wenyi, KAO, Tzu-Yorn
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Adult attachment, psychological stress, and quality of life: insights into Italian veterinary medicine students’ mental health

open access: yesBMC Psychology
Background Veterinary medicine students face distinctive challenges, such as exposure to animal suffering and academic pressures, which can adversely affect their quality of life (QoL), particularly regarding mental health.
Anna Panzeri   +7 more
doaj   +1 more source

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