MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Frontiers in PsychologyBackgroundSocial exclusion—being ignored, rejected, or excluded in social interactions—is a prevalent interpersonal stressor among college students, yet the specific mechanisms linking exclusion to long-term interpersonal difficulties remain poorly ...
Yi Liu, Pan Chen, Peng Lei, Wei Tang
doaj +1 more source
CIIC Submission - Advisory Committee Cultural Policy Response - October 2011.pdf
, 2015 Creative Industries Innovation Centre's submission for the National Cultural Policy review in October 2011, issuing six recommendations for future cultural policy.
Creative Industries Innovation Centre
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The ‘Cultural Industries’: A Clash of Basic Values? A Comparative Study of the EU and the NAFTA in Light of the WTO. EDAP 4/2004 [PDF]
, 2004 Originally coined in the 1940s by protagonists of the Frankfurt School, the concept of ‘culture industry’ was gradually transformed from a derogatory term into the potentially more constructive concept ‘cultural industries’ in the context of the global ...
Neuwirth, Rostam J.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Retracted: Static and Dynamic Demonstration of the Ecological Level of Ethnic Cultural Industries Based on the Internet of Things and Environmental Responsibility. [PDF]
J Environ Public Health, 2023 Environmental And Public Health JO.
europepmc +1 more source
CULTURAL-PRODUCTS INDUSTRIES AND URBAN ECONOMIC DEVELOPMENT: PROSPECTS FOR GROWTH AND MARKET CONTESTATION IN GLOBAL CONTEXT [PDF]
The paper opens with a brief definition of the cultural economy. A first generation of local economic development policy approaches based on place-marketing and associated initiatives is described.
Allen J Scott
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Conjunctions of resilience and the Covid-19 crisis of the creative cultural industries. [PDF]
Int J Cult Stud, 2022 Yue A.
europepmc +1 more source