Results 51 to 60 of about 4,648,312 (258)

Towards a 'new equilibrium': The economics and politics of the creative industries in Singapore [PDF]

open access: yes, 2006
On 26 September 2002, as Singapore faced up to its worst economic year since attaining full political independence in 1965, the Creative Industries Working Group (CIWG) of the Economic Review Committee (ERC), a governmentappointed, high-level body tasked
Terence Lee, Lee, Terence, Lee, T.
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Decoding “China”: a cross-cultural interpretation based on online comments of China’s mega projects III

open access: yesFrontiers in Communication
IntroductionAgainst the backdrop of globalisation, the cross-cultural communication effects of China's national narrative remain a complex and crucial issue.
Xiezhen Li, Fujiao Mao, Zehua Xu
doaj   +1 more source

“It’s All about Working with the Story!”: On Movement Direction in Musicals. An Interview with Lucy Hind

open access: yesArts, 2020
Lucy Hind is a South African choreographer and movement director who lives in the UK. Her training was in choreography, mime and physical theatre at Rhodes University, South Africa.
George Rodosthenous
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The cultural industries of India

open access: yes
The Cultural Industries of India is the first book length study dedicated to the Indian cultural and creative industries. By covering specific aspects of the cultural and creative sectors in India– from film festivals to music and performing arts, from ...
Dasgupta, Rohit K., Clini, Clelia
core   +1 more source

Creativity, cultural studies, and services industries

open access: yes, 2004
While both the growth of services industries and the nature of creativity as a productive input are widely recognized, they are poorly understood. This paper considers the relationship between services industry growth and creativity inputs as part of a ...
Flew, Terry
core   +1 more source

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