Results 81 to 90 of about 64,913 (311)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The ‘Cultural Industries’: A Clash of Basic Values? A Comparative Study of the EU and the NAFTA in Light of the WTO. EDAP 4/2004 [PDF]
, 2004 Originally coined in the 1940s by protagonists of the Frankfurt School, the concept of ‘culture industry’ was gradually transformed from a derogatory term into the potentially more constructive concept ‘cultural industries’ in the context of the global ...
Neuwirth, Rostam J.
core
The impact of COVID-19 on cultural industries: An empirical research based on stock market returns. [PDF]
Front Public Health, 2022 Zhang R, Ji H, Pang Y, Suo L.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
BMC PsychologyBackground Veterinary medicine students face distinctive challenges, such as exposure to animal suffering and academic pressures, which can adversely affect their quality of life (QoL), particularly regarding mental health.
Anna Panzeri +7 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The relationship between communication and education through the creative personality of the teacher
Creativity Studies, 2019 The article focuses on the relationships of communication and educational processes, creativity aspects in the context of higher education. A creative personality of the teacher determines how smooth and efficient these relationships are.
Vida Navickienė +3 more
doaj +1 more source
CIIC Submission - City of Sydney Cultural Discussion Paper - May 2013.pdf
, 2015 Creative Industries Innovation Centre submission responding to the City of Sydney Cultural Policy Discussion Paper. The submission outlines the Creative Industries Innovation Centre?s support of the discussion paper's key principles, and focuses on two ...
Creative Industries Innovation Centre
core
A Literature Analysis of Consumer Privacy Protection in Augmented Reality Applications in Creative and Cultural Industries: A Text Mining Study. [PDF]
Front Psychol, 2022 Kang Y, Su YS.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source