Results 101 to 110 of about 783,916 (309)
ECONOMIC CONTRIBUTION OF COPYRIGHT-BASED INDUSTRIES AND IMPACT ON EMPLOYMENT AND PERFORMANCE INDICATORS IN KNOWLEDGE-BASED SOCIETY DEVELOPING IN ROMANIA [PDF]
The economic dimension of copyright-based industries sector in Romania is becoming of higher interest, on the one hand, for policy-makers taking into consideration its increasing contribution to GDP, employment, foreign trade and investment and, on the ...
Gheorghe ZAMAN, Valentina VASILE
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Literature Review of the Definition, Size and Turnover of the Creative Industries and Micro-Businesses in Scotland: Preliminary Research [PDF]
, 2013 This research seeks to review, evaluate and clarify the findings of five recent reports in relation to the discussion paper Creative Industries in Scotland.
Sorensen, Inge
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Humanities & Social Sciences CommunicationsSerious games in education are often tied to digital learning environments, which require complex gamified content and systems to enhance students’ motivation.
Chong-Wen Chen
doaj +1 more source
Research on the Digital Preservation of Architectural Heritage Based on Virtual Reality Technology
BuildingsAs a representative of the scientific and technological achievements of the new era, the overall development of virtual reality (VR) technology is becoming increasingly refined, which provides new development ideas and technical support in the field of ...
Haohua Zheng +4 more
doaj +1 more source
Productivity Growth in Canadian and U.S. Regulated Industries [PDF]
This article compares the productivity growth of a set of Canadian and U.S. regulated industries. Using data from Statistics Canada’s KLEMS database and the U.S.
Amélie Lafrance, Wulong Gu
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Continuity in EducationDespite the important role played by psychologists working with adolescent cancer patients in addressing adolescent-specific issues, there are few data concerning their professional, emotional, and relational experience. Using an open-ended questionnaire,
Cristiana Punzi +2 more
doaj +1 more source