Results 131 to 140 of about 1,535,014 (362)
The impact of culture on career development of women in construction [PDF]
The construction industry is the most male dominated industry and displays a macho culture, where relationships are characterized by argument, conflict and crisis. Male values are the norm and are rewarded and the expectation is that career achievement
Amaratunga, Dilanthi +2 more
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Proximities and innovation : evidence from the Indian IT industry in Bangalore [PDF]
Much has been written on the success of the Indian software industry, enumerating systemic factors like first-class higher education and research institutions, both public and private; low labour costs, stimulating (state) policies etc. However, although
Täube, Florian Arun
core
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Indústria cultural, biopolítica e educação
Resumo O artigo visa a repensar o impacto de atuação da indústria cultural na educação, à luz do conceito de dispositivo, de acordo com os preceitos da biopolítica. Para tanto, lança mão de determinados processos advindos do aparato da indústria cultural,
Amarildo Luiz Trevisan +1 more
doaj +1 more source
Measurement and Model Construction of Tourism Industry and Cultural Industry's Interactive Convergence [PDF]
Haiyan Zhu
openalex +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

