Results 21 to 30 of about 6,600,071 (309)

State regulation as a factor of social significance of China’s modern culture industry

open access: yesВестник университета, 2022
The article is based on the study of state-party normative documents, such as the National Cultural Development Plan, The Cultural Industries Reinvigoration Plan, the National Economic and Social Development Plans China’s National Economic and Social ...
L. V. Filindash
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Evaluating the Impact of Presentation on Learning and Narrative in AR of Cultural Heritage

open access: yesIEEE Access
Cultural heritage exhibits an inherent relationship among various historical concepts and events. Previous studies that integrate augmented reality with cultural heritage have recognized AR as an effective tool for experiencing and learning about ...
Eunji Yoo, Jeongmin Yu
doaj   +1 more source

Sinemanın Denetimsiz Teknolojiyle Sınavı: Yapay Zeka’nın Film Endüstrisine Etkisi

open access: yesTürkiye Film Araştırmaları Dergisi, 2023
Teknolojinin hızla geliştiği günümüzde yapay zekâ çoğu alanda olduğu gibi sinemada da kendine yer bulmuştur. Özellikle son yıllarda yapay zekâ, sinema sektöründe üretimi kolaylaştırdığı için tercih sebebi haline gelmiştir.
Ayça Coşkuner
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Network Structural Characteristics and Influencing Factors of the Intercity Expansion of Chinese Time-Honored Brand Enterprises

open access: yesRedai dili
Chinese time-honored brands not only have the attributes of commodity economy but also cultural value, which is an important carrier of urban consumption.
Wan Chunlin, Liu Dajun
doaj   +1 more source

The impact of COVID-19 on cultural industries: An empirical research based on stock market returns

open access: yesFrontiers in Public Health, 2022
The COVID-19 virus has challenged the development of the cultural industries seriously, so far, however few studies have used empirical methods to analyze the impact of the pandemic on the overall cultural industries.
Rong Zhang   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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