Results 41 to 50 of about 6,600,071 (309)

The whole genome assembly and evolution analyze of carmine radish (Raphanus sativus L.) Mitochondrion

open access: yesMitochondrial DNA. Part B. Resources, 2020
Carmine radish, which contained a high natural red pigment (red radish pigment), was peculiar produced in Fuling, Chongqing City. Here, the complete nucleotide sequences of the mitochondrial (mt) genome of carmine radish (Raphanus sativus L.) have been ...
Hua Peng, Jian Gao
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tourism development and ecological impact assessment based on fuzzy TOPSIS method

open access: yesDiscover Artificial Intelligence
The growth of tourism is essential for economic development and the dissemination of cultural ideas; however, it also creates significant environmental problems that necessitate thorough remedial action.
Baohui Zhang, Huijun Xiao, Jinqing Zhang
doaj   +1 more source

Optimized CNN-based facial analysis for depression detection: Managing mental disorder in education

open access: yesBrain Research Bulletin
Major Depressive Disorder (MDD) is frequently under-identified in educational contexts, including arts and design programs, where limited clinical resources and privacy concerns restrict routine screening.
Mengqiu Wang   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Date estimation of fabrication and repair of Color garments encouragement banner

open access: yesFashion and Textiles
The Color Garments Encouragement Banner was designated a Korean Heritage in 2014 to recognize it as the most significant object of the color garments encouragement campaign.
Seonghee Pak, Boyeon An, Changsang Yun
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Agricultural socialized services in China’s smallholder farming systems: a systematic review of service types, benefits, and measurement challenges

open access: yesFrontiers in Agronomy
This review investigates the existing research on agricultural socialized services (ASS), focusing on their benefits to smallholder farmers and the barriers these farmers encounter in accessing such services. ASS are vital to modern agricultural systems,
Rong Zeng   +9 more
doaj   +1 more source

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