Results 41 to 50 of about 1,539,709 (312)

Organizational cultures: Obstacles to women in the UK construction industry [PDF]

, 2012
The global economic downturn coupled with recent changes in UK law have led to a sizable reduction in public sector funding. As a result, both public and private sector organizations are under greater pressure to provide evidence of their activities in ...
Alvesson, Barthorpe, Cameron, Chan, Chartered Institute of Building (CIOB), Dainty, Gale, Gale, Gershon, Giddens, Glaser, Gurjao, Hofstede, Hofstede, Levene, McSweeney, Moulettes, Peters, Schein, Schultz, Smircich, Taylor, Worrall, Worrall   +23 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The "52 week, 24 hour" university [PDF]

, 2014
The article seeks to consider the cultural and educational implications of ignoring times for pause and reflection by moving to service industry model of delivery higher education based on market ...
Ressel, James
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Hanfu: a systematic literature review integrating cultural tourism, digital technology, and national identity

Frontiers in Communication
Hanfu is one of the dominant traditional clothing cultures in China. However, current scholarly understanding of the Hanfu movement remains fragmented.
Yuhan He, Yuhan He, Baozhong Cai, Yonas Derebe, Meseret C. Abate   +4 more
doaj   +1 more source

Organizational Culture: Case of the Finnish Construction Industry [PDF]

, 2018
Academic literature has long recognized the correlation between a company’s organizational culture and its quality performance. The Finnish construction industry is still a highly human powered industry, and thus, organizational culture is seen to have a
Ali-Löytty, Simo, Junnonen, Juha-Matti, Teräväinen, Ville Juhani   +2 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The influence factors of tour guides' professional identity and professional decision before and after the COVID-19 pandemic

Heliyon
The COVID-19 pandemic has significantly impacted the tourism sector, particularly tour guides (TGs), affecting their professional identity (TGPI) and intentions to return to work.
Wenwen Hu, Qing Yuan, Yaxi Wang, Nan Chen   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The rise of a new cultural products industry cluster in Germany : the case of the Leipzig media industry [PDF]

, 2005
Over the past decade, a variety of studies have shown that other sectors in addition to high technology industries can provide a basis for regional growth and income and employment opportunities.
Bathelt, Harald
core