Results 41 to 50 of about 6,848,042 (258)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

The effect of rural tourism on rural prosperity: evidence from China on agricultural labor productivity, incomes, and household food consumption

open access: yesFrontiers in Sustainable Food Systems
Policy support in China has disproportionately favored rural tourism as a core pillar of rural revitalization. However, its net effect on agricultural labor productivity, rural income, and household consumption remains empirically untested.
Liu Jin   +3 more
doaj   +1 more source

The impact of COVID-19 on cultural industries: An empirical research based on stock market returns

open access: yesFrontiers in Public Health, 2022
The COVID-19 virus has challenged the development of the cultural industries seriously, so far, however few studies have used empirical methods to analyze the impact of the pandemic on the overall cultural industries.
Rong Zhang   +3 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

State and Current Trends in the Development of Personal Brands in Show Business

open access: yesSocio-Cultural Management Journal, 2023
Introduction. Today, Ukraine's economy is going through difficult times, which affects all areas of human activity. Show business, as a sphere of the cultural economy, is experiencing its own specific changes as a result.
Daryna Solonyna
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

California Low-Level Radioactive Waste Disposal Project Cultural Resources Surveying: Ethnographic Resources Candidate Site Selection Phase

open access: yes, 1987
This report describes the results of an ethnographic study performed by Cultural Systems Research, Incorporated (CSRI) for US Ecology, Inc. The study was part of US Ecology's efforts to select a site for the disposal of Low Level Radioactive Waste (LLRW)
Stoffle, Richard W.   +1 more
core   +2 more sources

Hanfu: a systematic literature review integrating cultural tourism, digital technology, and national identity

open access: yesFrontiers in Communication
Hanfu is one of the dominant traditional clothing cultures in China. However, current scholarly understanding of the Hanfu movement remains fragmented.
Yuhan He   +4 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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