Results 51 to 60 of about 6,600,071 (309)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Heritage SciencePalm leaf manuscripts (PLMs), venerable historical artefacts containing Buddhist scriptures, history, mathematics and literature, which are carried by palm leaves (Corypha umbraculifera) and are highly susceptible to microbial degradation during ...
Shimin Chu, Lanying Lin, Xingling Tian
doaj +1 more source
Acta PsychologicaThe rapid growth of short-form video platforms presents both potential public health considerations and new avenues for social engagement, yet longitudinal evidence on how different patterns of short video use are linked to youth mental health remains ...
Dong Zhou, Li-Min Lin
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
IEEE AccessWith the acceleration of globalization, the development of the tourism industry increasingly relies on cross-border collaboration, and the digital economy can provide new opportunities for the tourism industry and promote the global application of new ...
Yu Xia
doaj +1 more source
BCC presents 1984-85 cultural arts series
, 2010 Fall Semester posting of the Cultural Arts Series; Spring Semester posting of the Cultural Arts Series.Various events posted for the Black Cultural Center’s Cultural Arts Series of 1984-85.Photos of Phyllis Hyman and Alvin Poussaint included along with a
Purdue University. Black Cultural Center;
core