Results 51 to 60 of about 1,539,709 (312)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Tourism development and ecological impact assessment based on fuzzy TOPSIS method

Discover Artificial Intelligence
The growth of tourism is essential for economic development and the dissemination of cultural ideas; however, it also creates significant environmental problems that necessitate thorough remedial action.
Baohui Zhang, Huijun Xiao, Jinqing Zhang
doaj   +1 more source

Optimized CNN-based facial analysis for depression detection: Managing mental disorder in education

Brain Research Bulletin
Major Depressive Disorder (MDD) is frequently under-identified in educational contexts, including arts and design programs, where limited clinical resources and privacy concerns restrict routine screening.
Mengqiu Wang, Yanxia Wu, Khosro Rezaee, M. Khosravi   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Date estimation of fabrication and repair of Color garments encouragement banner

Fashion and Textiles
The Color Garments Encouragement Banner was designated a Korean Heritage in 2014 to recognize it as the most significant object of the color garments encouragement campaign.
Seonghee Pak, Boyeon An, Changsang Yun
doaj   +1 more source

Cultural realignment, islands and the influence of tourism: A new conceptual approach [PDF]

, 2013
This article introduces a new concept: ‘cultural realignment’, which embraces phenomena such as cultural representation, interpretation, stereotyping and branding.
MacLeod, Donald
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Agricultural socialized services in China’s smallholder farming systems: a systematic review of service types, benefits, and measurement challenges

Frontiers in Agronomy
This review investigates the existing research on agricultural socialized services (ASS), focusing on their benefits to smallholder farmers and the barriers these farmers encounter in accessing such services. ASS are vital to modern agricultural systems,
Rong Zeng, Meseret C. Abate, Cai Baozhong, Amsalu K. Addis, Xiangyun Yi, Shaoping Jiang, Xu Yan, Betelhem A. Geremew, Amsalu N. Alamerew, Amsalu N. Alamerew   +9 more
doaj   +1 more source

Navigating the Copyright Landscape: Iran's Journey towards Global Integration [PDF]

International Journal of Information Science and Management
This study aims to explore the issues, factors, and outcomes of Iran's accession to international copyright treaties, offering practical recommendations. The research uses a qualitative approach with grounded theory methodology.
Dariush Matlabi
doaj   +1 more source

Was it Doomsday? First Wave of the COVID-19 Pandemic Impact on the Polish Cultural Industry

Economics and Culture, 2022
Research purpose. The COVID-19 pandemic has become a theme of the research on the functioning of the economy and particular industries. The same concerns were raised regarding the issue of the cultural industry.
Komańda Marcin
doaj   +1 more source