Results 61 to 70 of about 8,996,586 (398)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Mapping State Cultural Policy: The State of Washington [PDF]

open access: yes, 2003
State-level funding for the arts, humanities, heritage, and allied forms of culture is an important source of financial support, dwarfing the aid provided by the National Endowment for the Arts.
Colleen Grogan   +5 more
core  

'Impact', 'value' and 'bad economics' : making sense of the problem of value in the arts and humanities [PDF]

open access: yes, 2014
Questions around the value of the arts and humanities to the contemporary world, the benefits they are expected to bring to the society that supports them through funding have assumed an increased centrality within a number of disciplines, not limited to
Belfiore, Eleonora
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Anti-Space: the political complexion of an inner city art gallery

open access: yesJournal of Architecture and Urbanism, 2014
The subject of this paper is an inner city artist-run gallery called Eastside Projects. As part of an historical trend in artistrun spaces, Eastside Projects have innovated a strategic approach to post-industrial space, their location and role within the
Jonathan P. Vickery
doaj   +1 more source

Mapping cultural policy in Portugal: From incentives to crisis

open access: yesCultural Policy in Ibero-America, 2018
Taking into account the course of cultural policy in democratic Portugal, and against the backdrop of the international crisis of 2008 and the sovereign debt crisis of 2011, this article seeks to interpret recent changes in the cultural sector in ...
J. L. Garcia   +5 more
semanticscholar   +1 more source

The SNP, cultural policy and the idea of the "creative economy" [PDF]

open access: yes, 2009
No abstract ...
Schlesinger, P.
core   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Icelandic Cultural Policy [PDF]

open access: yes, 2013
In Mars 2013 the Icelandic Parliament decided upon the first formal “Icelandic Cultural Policy”. In this article that document is examined in light of debates concerning the concept of deliberate cultural policy making.
Sigurjonsson, Njordur
core   +1 more source

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