Results 91 to 100 of about 1,446,638 (307)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Discourse Dynamics and Cultural Representation in Indonesian Cinema: A Case Study of Sayap-Sayap Patah Dua

open access: yesJournal of English Teaching and Applied Linguistics
This study investigates the discourse dynamics and cultural representations conveyed through Indonesian cinema, with a specific focus on the film Sayap-Sayap Patah Dua. The primary research problem centers on understanding how cinematic discourses employ
Binti Qani'ah
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

From Cousin Joe to the Comoros: Orthography and the Politics of Choice in Africa and African America [PDF]

open access: yes, 2003
This paper explores issues of orthographic representation in two different projects, in two different locations, and draws some general conclusions about the role of an outsider linguistic anthropologist in working with individuals and their data.
Ottenheimer, Harriet Joseph
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Curating the invisible: contemporary art practices and the production of meaning in Eastern Europe. [PDF]

open access: yes, 2008
Previously in the University eprints HAIRST pilot service at http://eprints.st-andrews.ac.uk/archive/00000394/Article 6 of 6 in an issue devoted to the visual culture of South Eastern EuropeThis article addresses the system of art and the issue of ...
Stamenkovic, Marko.
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A study of cultural representation in Hokkien (Southern Min) textbooks

open access: yesFrontiers in Education
This research employed a framework for analyzing cultural representations within textbooks to focus on the three dimensions of geographical contexts, types of cultures and modes of presentation.
Yuannan Huang, Haoyan Song
doaj   +1 more source

ANTHROPOLOGICAL COMPREHENSION OF A WOMAN-AUTHOR AS THE SUBJECT OF CULTURE THROUGH THE PRISM OF LANGUAGE AND LITERATURE (GENDER ASPECT)

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2019
Purpose. To study the phenomenon of a woman-author as a subject of culture and philosophy from a development of literary aspect in the works both Western and Ukrainian scientists.
I. A. Koliieva, T. A. Kuptsova
doaj   +1 more source

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