Results 121 to 130 of about 1,446,638 (307)
Digital Atolls: Cultural Imaginaries and the Representation of the Maldives in Video Games
Kultura Media TeologiaThe aim of this article is to analyze representations of the Maldives in video games from a cultural studies and postcolonial perspective. The study treats the archipelago as a unique cultural phenomenon whose depiction in digital narratives is shaped by
Krzysztof Chmielewski
doaj +1 more source
Representation of cultural stereotypes in ukrainian advertising [PDF]
, 2014 У статті розглядається репрезентація культурних стереотипів в українській рекламі. Особлива увага приділяється аналізу використання у рекламних повідомленнях патріотичних мотивів та елементів національного колориту.
Yanenko, Yaroslav Vasylovych +2 more
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Whose Crying Game? One Woman of Color\u27s Reflection on Representations of Men of Color in Contemporary Film [PDF]
, 1994 This film review of The Crying Game critically interrogates the politics of representation and domination which spectacleize Black male bodies. Working out of her location as an Asian American woman who is sensitive to the cinematic and everyday ...
Sciachitano, Marian M.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The Economics of Cultural Formation of Preferences [PDF]
This paper introduces a generalized representation of the formation of continuous preferences (which can reflect different intensities). The preference intensity that a child adopts is formed as the collective outcome of all role models for preference ...
Michael M. Pichler
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Gradually European and Diminishingly Balkan
Annales, Series Historia et SociologiaThis paper explores the cultural representation of Croatia in international guidebooks published during the process of the country’s EU-accession (2003–2013).
Zlatan Krajina
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source