Results 111 to 120 of about 1,950,766 (306)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Cogent Social SciencesThis study investigates the impact of cultural practices within Ghanaian coastal communities on the cultural rights of small-scale fishers, with a focus on livelihood dynamics.
John Kwame Boateng +3 more
doaj +1 more source
Which Takes Precedence: Collective Rights or Culture? [PDF]
, 2015 This Paper claims that, contrary to the common assumption of Anglo-American jurists, collective rights are secondary to a analytically and experientially prior culture. Culture constitutes the identity and content of a collective right.
Conklin, William
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
THE IMPACT OF DIGITAL TECHNOLOGIES ON THE CULTURAL RIGHTS OF D/DEAF AND HARD-OF-HEARING PEOPLE
EudaimoniaDigital technologies permeate almost all spheres of human lives in contemporary times, affecting a number of aspects of people’s lives. Such is the case with cultural rights as well, especially in the cases of certain groups.
Sofija Lekić
doaj +1 more source
Citizenship studies: An introduction [PDF]
, 2002 About the book: From women's rights, civil rights, and sexual rights for gays and lesbians to disability rights and language rights, we have experienced in the past few decades a major trend in Western nation-states towards new claims for inclusion. This
Isin, Engin F., Turner, Bryan S.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Cultural rights in the Republic of Serbia: Current state and perspectives [PDF]
Strani pravni život, 2019 Cultural rights are one of the least developed groups of human rights. It is very controversial which rights are included in cultural rights. However, despite their vagueness, their importance is increasing today.
Nikolić Aleksa D.
doaj
Women Reproductive Rights in India: Prospective Future. [PDF]
, 2011 Reproductive rights were established as a subset of the human rights. Parents have a basic human right to determine freely and responsibly the number and the spacing of their children.
Bhat, US +4 more
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