Results 91 to 100 of about 1,950,766 (306)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Human Right to Take Part in Cultural Life
Review of European and Comparative LawThe human right to take part in cultural life is rooted in dignity of the person. Cultural rights form an integral part of human rights and, like all other rights, are universal, indivisible and interdependent, that is why respecting them is essential ...
Krzysztof Orzeszyna
doaj +1 more source
Litigating reproductive health rights in the inter-American system: what does a winning case look like? [PDF]
, 2014 Remedies and reparation measures emerging from the Inter-American System of Human Rights in reproductive health cases have consistently highlighted the need to develop and subsequently implement, non-repetition remedies that protect, promote and fulfill ...
O'Connell, Ciara
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Economics for Human Rights [PDF]
The Subprime Crash that started capitalism’s latest crisis was mainly a proxy for an inexistent housing policy which would benefit many impoverished middle class families.
Manuel Couret Branco
core
Gendercide and the Cultural Context of Sex Trafficking in China [PDF]
, 2008 This paper discusses the interconnection of historic, legal, and cultural contexts that result in the perpetuation of discrimination against women in Chinese society.
Edwards, Christie J,, Tiefenbrun, Susan
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Interaction Between Law, Economics and Indigenous Cultures: The Ocumicho Devils
Oñati Socio-Legal Series, 2010 Seeing cultural rights as the rights that people have to actively involve with and develop their culture and that one important way to do this is by participating of the many art forms in which the cultural identity can be expressed, this research ...
Lucero Ibarra Rojas
doaj
Austerity and Human Rights Law: Towards a Rights-Based Approach to Austerity Policy, a Case Study of Greece [PDF]
, 2015 This Note analyzes the legal framework for the protection of the right to work under national and international laws, and the limitations for Greece regarding the implementation of austerity measures that result in causing retrogression in the enjoyment ...
Housos, Katerina
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source