Results 81 to 90 of about 1,950,766 (306)

Collective Management of Copyrights and Human Rights: An Uneasy Alliance Revisited [PDF]

open access: yes, 2010
This essay analyzes the “creators’ rights” provisions of the International Covenant on Economic Social and Cultural Rights (ICESCR) in the context of the collective administration of copyright and neighboring rights and the policies and practices of ...
Helfer, Laurence R.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

"Internet Access as a New Human Right? State of the Art on the Threshold of 2020"

open access: yesPrzegląd Prawniczy Uniwersytetu im. Adama Mickiewicza, 2018
The aim of this study is to analyze the role that the Internet plays in the enjoyment of human rights and answer the question of whether we may be in the process of recog-nizing a new right, namely the right to Internet access. The conclusions are built
Łukasz Szoszkiewicz
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Mthembu v Letsela: The non-decision [PDF]

open access: yesPotchefstroom Electronic Law Journal, 2001
The debate concerning the apparent conflict between equality (section 9 of the Constitution of the Republic of South Africa 108 of 1996) and culture (sections 30 and 31 of the 1996 Constitution) is ongoing.
AM Janse van Rensburg
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

BATIK INDUSTRY OF INDONESIA: THE RISE, FALL AND PROSPECTS [PDF]

open access: yes
Batik clothes are a society national cultural heritage of Indonesia. In the last four decades has experienced profit, loss and legal intellectual property rights disputes in its business development.
Budiono Gatut, Vincent Aryanto
core  

Cultural Environmentalism and the Constructed Commons [PDF]

open access: yes, 2007
Van Houweling explores both the benefits and failings of conservation easements on land on the one hand and the licensing commons on the other. Conservation easement The tools of cultural environmentalism in the lights of objections to conservation ...
Van Houweling, Molly Shaffer
core   +1 more source

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