Results 71 to 80 of about 126,680 (264)

The Human Right to Take Part in Cultural Life

open access: yesReview of European and Comparative Law
The human right to take part in cultural life is rooted in dignity of the person. Cultural rights form an integral part of human rights and, like all other rights, are universal, indivisible and interdependent, that is why respecting them is essential ...
Krzysztof Orzeszyna
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The culture of the cultural rights

open access: yes, 2020
The essay opens with a review of the uncertainties in the definition of the concept of “cultural rights”, which is strongly connected with the undeterminedness of the concept of “culture” itself. The A. performs a philological comparative study on the concept of culture in the meaning that is relevant with regard to the universality of cultural rights.
openaire   +1 more source

Rights of Culture, Rights of Conscience

open access: yes, 2006
In this contribution I take up a particularly troubling issue in the theory of human rights. It is the issue of intervention to defend or uphold — or re-assert and re-establish — human rights. The issue is a troubling one because intervention in the affairs of others is always something we should be wary of, not least because history is full of unhappy
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Interaction Between Law, Economics and Indigenous Cultures: The Ocumicho Devils

open access: yesOñati Socio-Legal Series, 2010
Seeing cultural rights as the rights that people have to actively involve with and develop their culture and that one important way to do this is by participating of the many art forms in which the cultural identity can be expressed, this research ...
Lucero Ibarra Rojas
doaj  

"Internet Access as a New Human Right? State of the Art on the Threshold of 2020"

open access: yesPrzegląd Prawniczy Uniwersytetu im. Adama Mickiewicza, 2018
The aim of this study is to analyze the role that the Internet plays in the enjoyment of human rights and answer the question of whether we may be in the process of recog-nizing a new right, namely the right to Internet access. The conclusions are built
Łukasz Szoszkiewicz
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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