Results 151 to 160 of about 188,093 (303)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Exploring cultural sensitivity during distance simulations in pediatric emergency medicine. [PDF]

AEM Educ Train, 2023
Fayyaz J, Jaeger M, Takundwa P, Iqbal AU, Khatri A, Ali S, Mukhtar S, Saleem SG, Whitfill T, Ali I, Duff JP, Kardong-Edgren SS, Gross IT.   +12 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Cultural Awareness Sensitivity Training

, 2002
In this study, employees of the Federal Correctional Institution in Ashland, Kentucky; the Federal Medical Center in Rochester, Minnesota; and the Federal Correctional Institution in Milan, Michigan were surveyed to determine the need for a Cultural ...
Underwood, William L.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Cultural sensitivity and patient-centered care regarding incense and candle smoke emissions. [PDF]

Front Allergy
Lam G, Nejat C, Lee-Wong MF.
europepmc   +1 more source

Examining the Relationship of Cultural Sensitivity, Self-Esteem, and Cultural Identities

This study examines qualities of self-esteem and its relationship to the process of self-reflection and sensitivity development. The intercultural sensitivity development model highlights the exploration of cognitive and affective processes as the ...
Black, Jeanneka
core  

CULTURAL SENSITIVITY AND ELDER ABUSE: CONSIDERATIONS FOR SOCIAL WORK PRACTICE

, 2014
The purpose of this study was to explore how social workers identify elder abuse, factors they find contribute to or protect from elder abuse, and cultural considerations they identify as important.
Bernardo, Katherine R
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Reevaluating the assessment of nonverbal behavior in psychosis symptomatology: A call for cultural sensitivity. [PDF]

Schizophr Res
Schuch JM, Pratt DN, Haase CM, Qu Y, Mittal VA.   +4 more
europepmc   +1 more source