Results 161 to 170 of about 859,177 (304)

Improving intercultural communication skills: A challenge facing institutions of higher education in the 21st century [PDF]

open access: yes
Following discussion of the rationales for improving students' intercultural communication skills, this article described how the professors at the University of Rhode Island and their counterparts around the world use the Internet as a mechanism for ...
Kim, Chai K.
core  

Health Social Workers in Promoting Mental Health Equity: Voice and Agency for the Marginalized

open access: yesSocial Work and Society
Globally, 1 in 4 persons have mental health issues at some point in life. However, the mental health services are not easily available, accessible and affordable to all strata of the society with varying socio-economic and cultural backgrounds.
Chandramathi Ramaswamy   +4 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

An Interactive Game with Virtual Reality Immersion to Improve Cultural Sensitivity in Health Care. [PDF]

open access: yesHealth Equity, 2022
Hershberger PJ   +12 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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