Results 61 to 70 of about 168,087 (258)

Managing the Needs of Orphans and Vulnerable Children in Mainstream Rural Schools: An Ethnopsychology Informed Approach [PDF]

E-Journal of Humanities, Arts and Social Sciences
Orphans and vulnerable children (OVC) in mainstream rural schools encounter unique challenges stemming from loss, economic instability, and disrupted familial structures.
Nowell Chidakwa, Fumane Portia Khanare
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Intergroup anxiety, cultural sensitivity and socio-cultural diverse leaders’ effectiveness

International Journal of Psychological Research, 2015
This intended to analyze differences in the level of perception –of general population participants- in regards to leaders with diverse socio-cultural characteristics (gender, sexual orientation, religious affiliation, nationality) and also verify by ...
María Laura Lupano Peruginni, Alejandro Castro Solano   +1 more
doaj  

Culture and Behaviour Management of Children in the Dental Clinic: A Scoping Review

Dentistry Journal
Cultural norms, beliefs, and practices influence parental expectations, children’s responses, and the acceptance of behaviour management techniques (BMTs) in paediatric dentistry. Despite this, the existing guidelines often adopt a standardized approach,
Adebola Oluyemisi Ehizele, Love Bukola Ayamolowo, Adeyinka Ishola, Moréniké Oluwátóyìn Foláyan   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Speech and language therapists’ perceptions of corporate practice in South Africa

South African Journal of Communication Disorders
Background: Corporate speech and language therapy (CSALT) is an emerging field that extends the role of speech and language therapists (SALTs) into corporate environments, enhancing workplace communication and interpersonal skills.
Ntandoyenkosi L. Msomi, Suvishka Barath, Andrew J. Ross   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Karakter yang Diperlukan Dunia Kerja dalam Menghadapi Pasar Bebas Asean 2015

Humaniora, 2014
ASEAN Free Trade will be started in 2015 and at that time global competition, especially between the countries of ASEAN would be more competititive.
Christofora Megawati Tirtawinata
doaj  

Cultural sensitivity and sports: a case study of college students

Physical Education of Students
Background and Study Aim. Sports participation plays a significant role in promoting physical and mental well-being. However, in many conservative societies, cultural sensitivity greatly impacts women's engagement in physical activities.
Sm Farooque, Sobena Begum, Ahsan Huda Yumkhaibam, Sanjib Kumar Bhowmik   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source