Results 81 to 90 of about 144,880 (304)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Does education engender cultural values that matter for economic growth? [PDF]

open access: yes
Empirical research has shown that cultural values matter for economic growth and has specifically identified the achievement motivation as an aspect of culture that engenders economic growth. If specific cultural values engender economic growth, how then
Prosper F. Bangwayo-Skeete   +2 more
core  

Teaching methods of traditional dances in cultural-artistic societies: Case study of children's groups from Pančevo and Bačka Palanka [PDF]

open access: yesZbornik Radova Akademije Umetnosti, 2018
Dance, as a syncretic entity of movement and music, has been present in the life of people since ancient times. Through dance, people express their emotions, aesthetic needs, physical and musical abilities. Besides its expressive function, dance can also
Đačanin Svetlana
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Cross-cultural influence on diffusion and adoption of innovation: An exploratory case study to investigate the social-cultural barriers [PDF]

open access: yes, 2011
The development of science and technology increasing rapidly; in many cases advantageous innovations find obstacles for their establishment and in some others they simply fail. The authors of this paper demonstrate that the reason this may happen, is not
Ali, M, Deligiannaki, A
core  

Somatization vs. Psychologization of Emotional Distress: A Paradigmatic Example for Cultural Psychopathology [PDF]

open access: yes, 2002
This paper describes the developing area of cultural psychopathology, an interdisciplinary field of study focusing on the ways in which cultural factors contribute to the experience and expression of psychological distress.
Jian Yang   +5 more
core   +2 more sources

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Cultural Foundations of Autocracy and Their Amendment: What Can Higher Education Institutions Do? [PDF]

open access: yesRomanian Journal of European Affairs, 2012
The paper examines the foundations of the societies in Central Asia (CA) and their impact on politics, recalls similarities with Central and Eastern Europe (CEE), attempting to make recommendations for the societies’ advancement.
Iulian Oneașcă
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy