Results 61 to 70 of about 144,880 (304)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Evolution of Cultural Traits Occurs at Similar Relative Rates in Different World Regions [PDF]

open access: yes, 2014
A fundamental issue in understanding human diversity is whether or not there are regular patterns and processes involved in cultural change. Theoretical and mathematical models of cultural evolution have been developed and are increasingly being used and
Currie, TE, Mace, R
core  

Cultural influence on metacognition: comparison across three societies

open access: yesHumanities & Social Sciences Communications
We tested the hypothesis that metacognition—the ability to evaluate one’s own cognitive processes and mental states—is modulated by cultural values. We used retrospective confidence ratings to objectively measure metacognition in a mental rotation task ...
Mikhail Ordin   +4 more
doaj   +1 more source

Dialog międzykulturowy w społeczeństwach pluralistycznych

open access: yesPoliteja, 2014
Intercultural dialogue in pluralistic societies Multiculturalism is the wide social and ideological context for the transcultural and cross cultural relations.
Tadeusz Paleczny
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Attitudes towards shoplifting: a preliminary cross-cultural study of consumers [PDF]

open access: yes, 2013
Shoplifting has a substantial impact on retailers, consumers and wider society, yet we know very little about people‟s attitudes towards this behaviour, especially from a non-Western perspective.
Whysall, P   +7 more
core  

Family: Variations and Changes Across Cultures [PDF]

open access: yes, 2003
In order to study psychological phenomena cross-culturally, it is necessary to understand the different types of family in cultures throughout the world and also how family types are related to cultural features of societies.
Georgas, James, James Georgas
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Leadership, Violence, and Warfare in Small Societies [PDF]

open access: yes
Multi-agent simulation was used to study the effect of simple models of leadership on interpersonal violence and warfare in small societies. Agents occupied a two dimensional landscape containing villages and food sources.
Stephen Younger
core  

Cultural Capital and Cultural Participation [PDF]

open access: yes, 2016
U radu se navode i analiziraju teorijski pristupi i istraţivački radovi kojima se pokušavaju objasniti trendovi u participaciju u kulturi u današnjim društvima.
Šljivečka, Ivan
core  

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