Results 141 to 150 of about 16,648,666 (313)
Parasites and politics: why cross-cultural studies must control for relatedness, proximity and covariation. [PDF]
Bromham L +4 more
europepmc +1 more source
Message from the President, Opening Ceremony Speech, Institute Overview, Organizational Chart, Membership, Some Preliminary Observations on the History of Chinese and Japanese Cultural Interaction, First International Symposium Considering the Potential ...
Institute, For Cultural Interaction Studies Kansai University +1 more
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Cultural studies : teori & praktik
salah satu masalah utama dalam upaya menyediakan sebuah buku teks bagi cultural studies yang matang (meski hanya tahap pertama) adalah menemukan dan menjelaskan basis supradisipliner, suatu ikatan longgar jaringan - jaringan atau metafora - metafora yang
Chris Barker
core
The idea of deep surfaces in cultural studies [PDF]
This paper argues that Cultural Studies has tended in the past to arrive at a methodological impasse by failing to adequately theorise the status of the object of a 'cultural' study.
Johnson, Laurie
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
ETHNOLINGUISTICS AND THE STUDY OF CULTURE [PDF]
openaire +2 more sources

