Results 151 to 160 of about 1,017,592 (316)
Parasites and politics: why cross-cultural studies must control for relatedness, proximity and covariation. [PDF]
R Soc Open Sci, 2018 Bromham L +4 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
They Do Things Differently There. Essays on Cultural History [PDF]
, 2015 This collection of Finnish essays in cultural history will be revelatory for anglophone readers. Pioneering in the study of cultural history as early as the nineteenth century, by the 1930s Finnish scholars already deployed the broad conception of ...
Johnson, Bruce, Kiiskinen, Harri (eds.)
core
Using Cross-Cultural Studies to Improve Evidence on Dementia Prevention: Lessons from the Special Issue Sponsored by the International Research Network on Dementia Prevention (IRNDP). [PDF]
J Alzheimers Dis, 2019 Glymour MM, Whitmer RA.
europepmc +1 more source
ETHNOLINGUISTICS AND THE STUDY OF CULTURE [PDF]
American Anthropologist, 1949 openaire +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2008 Message from the President, Opening Ceremony Speech, Institute Overview, Organizational Chart, Membership, Some Preliminary Observations on the History of Chinese and Japanese Cultural Interaction, First International Symposium Considering the Potential ...
Institute, For Cultural Interaction Studies Kansai University +1 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source