Results 261 to 270 of about 48,549,817 (363)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Bio-Archive of Cultural Heritage Microbiomes for Sustainable Conservation in the Multi-Omics Era. [PDF]
Adv Genet (Hoboken)Fu X, Wu F, Liu X.
europepmc +1 more source
Study on the impact of different cultural mediums on the viability of thawed boar spermatozoa
O. Y. Lyzohub +3 more
openalex +2 more sources
A Study of Cultural Tourism: The Case of Visitors to Prince Edward Island
, 2008 Sean Hennessey +3 more
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
To Be Bicultural Is to Be Friends? Associating Early Adolescents' Cultural Identities and Behaviors With Friendship Networks in Minority-Only Schools. [PDF]
J Community PsycholHillekens J, Stark TH, Phalet K.
europepmc +1 more source