Results 41 to 50 of about 518,211 (354)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Feeling Trauma: A Proposal for a New Approach to the Study of Post-traumatic Cinema

open access: yesKwartalnik Filmowy
The article explores the representation of cultural trauma in cinema, challenging the common perception of film’s inability to fully capture traumatic experiences.
Jakub Gortat
doaj   +1 more source

SENIOR CITIZENS OF THE PERM TERRITORY AND FEARS ASSOCIATED WITH NEW TECHNOLOGIES

open access: yesВестник археологии, антропологии и этнографии, 2019
The present article covers the formation and functioning of socio-cultural fears that have developed among pensioners from the provincial towns of the Perm Territory (Urals).
N.A. Shirinkina
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

THE CHERNOBYL ACCIDENT AS A CULTURAL TRAUMA OF UKRAINE

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2014
The article analyzes theoretical approaches to the study of the consequences of the Chernobyl tragedy in the context of cultural searches of modernity in the prospect of "memorial paradigm." The aim is to bring the concept of perception of the Chernobyl ...
Ya.O. Yakovlieva
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Bearing witness: working with clients who have experienced trauma - considerations for a person-centered approach to counseling [PDF]

open access: yes, 2007
This paper explores traumatic experience from both a cultural and neurophysiological perspective. An argument is developed to support and challenge the person-centered approach in working with clients who have experienced trauma.
Rutherford, Morna C.
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Cultural Trauma in Patricia Grace’s Potiki

open access: yesPolilog: Studia Neofilologiczne
After around a hundred years of British colonial domination New Zealand became an independent country in 1947. Yet, it took another thirty years for its native writers to regain the New Zealand voice and ‘write back,’ to (re)tell the story of the people
Ewa Kroplewska-Kuśnierz
doaj   +1 more source

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