Results 41 to 50 of about 4,423,570 (284)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
How pain becomes common? Cultural trauma as a process
Studia Humanitatis, 2018 The article reviews the process and peculiarities of the transition of personal trauma into cultural one. The diaries of inhabitants of the besieged Leningrad became the source for the research.
Golovashina Oksana Vladimirovna
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Using Cultural-Historical Theory to Explore Trauma among Refugee Populations in Europe [PDF]
, 2018 The psychological impact of atrocities endured by refugee populations is clear, with the literature reporting significantly high prevalence rates of post-traumatic stress disorder (PTSD).
Womersley, Gail, Kloetzer, Laure
core +1 more source
Political Youth Organisations, Music and National Identity in Contemporary Russia
Studies of Transition States and Societies, 2014 This article analyses the relationship between political youth organisations, music and national identity in contemporary Russia. It focuses on four of the most representative political youth groups present in the city of St. Petersburg – the Young Guard,
Chiara Pierobon
doaj
Cogent Arts & HumanitiesThe Spanish Civil War (1936-1939) was a cruel confrontation whose consequences were aggravated by Franco’s repression. One army corps that represents the suffering and, at the same time, the will for individual and collective recovery at its best is the ...
Carmen Marimón Llorca +1 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Czarne cierpienie, dekontekstualizacja i problemy współczesnego horroru rasowego
Studia FilmoznawczeThis article examines the problematic issues surrounding horror films that have addressed race since the release of Get Out. The article outlines the significance of Jordan Peele’s feature film debut, considering context of black horror, as well as the ...
Dominik Langiewicz
doaj +1 more source
Urban Ruins: Visuality of Social Meanings
Интеракция. Интервью. Интерпретация, 2023 Architectural ruins in the context of the urban landscape carry many meanings and functions: they reflect changes in fashion, security, cultural values, and show the peculiar struggle of urbanization and the “recapture” of abandoned places by plants and ...
Dmitrij Sergeevich Polikarpov +2 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source