Results 71 to 80 of about 14,735,798 (370)
{Excerpt} Some needs are common to all people—at all times and in all places. They are the need to make a living, the need for social organization, the need for knowledge and learning, the need for normative and metaphysical expression, and the need for ...
Serrat, Olivier
core +1 more source
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Culture and Institutions [PDF]
A growing body of empirical work measuring different types of cultural traits has shown that culture matters for a variety of economic outcomes. This paper focuses on one specific aspect of the relevance of culture: its relationship to institutions. We review work with a theoretical, empirical, and historical bent to assess the presence of a two-way ...
Alesina, Alberto, Giuliano, Paola
openaire +9 more sources
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Juxtaposition of Women, Culture, and Nature in Alice Walker's Possessing the Secret of Joy [PDF]
The present paper focuses on the tradition of women's circumsicion in the African tribe of Olinkan in Alice Walker's Possesing the Secret of Joy. The Olinkans are asked by the white settlers to stop women's mutilation, but Olinkan men continue this ...
Gholami, F. (Farzane) +2 more
core
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
What is Organisational Culture and How Can IT Be Managed Effectively [PDF]
Budaya organisasi merupakan salah satu faktor penting yang menentukan kesuksesan suatu organisasi dan memiliki dampak jangka panjang terhadap kinerja organisasi tersebut.
Aminah, A. (Aminah)
core
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source

