Results 51 to 60 of about 1,080,305 (313)

Exploring health literacy in developing economies: Perspectives and practices of health communication professionals in rural Nigeria

open access: yesHealth Literacy and Communication Open
Background Health literacy is widely recognised as a social determinant of health and a key factor in health communication and education, with low health literacy correlated with poor health outcomes and socioeconomic inequalities.
Onyinye Chiweta-Oduah, Steven Buchanan
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Patterns of Media Use and Reflections on Media among young Danes

open access: yesNordicom Review, 2015
The present article examines cross-media use among 10- to 16-year-old Danish children and adolescents. Our research interest is in identifying and affirming patterns among media use, gender and age. Using a methodological design that combines qualitative
Krogager Stinne Gunder Strøm   +2 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Knowledge Management as Imperative for Economic Growth and Development

open access: yesEconomic Analysis, 2015
We are now living in times of global business activity and the knowledge economy. Knowledge-based resources represent the organizational Know-how as the knowledge of employees, organizational production processes, and overall knowledge of one collective.
Vesna Baltezarević   +2 more
doaj  

Tool, companion or a catalyst force? Exploring sociotechnical imaginaries Within AI livestreams’ communities of practice

open access: yesBig Data & Society
How online communities of practice (CoPs) around artificial intelligence (AI) construct, construe, and shape sociotechnical imaginaries is relatively unexplored, as most studies focus on elite discourse in politics, technology, and the media.
Sacha Gutierrez   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Research on the effect of image size on real-time performance of robot vision positioning

open access: yesEURASIP Journal on Image and Video Processing, 2018
In order to improve the real-time performance of visual positioning of the indoor mobile robot, the researchers found that the shape and size of the positioned image have a great influence on the real-time performance of the positioning calculation.
Desheng Lyu, Heyang Xia, Chen Wang
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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