Results 31 to 40 of about 239,653 (217)

RATOVI I TOKOVI DEOSMANIZACIJE BALKANA (1912-1923) //WARS AND WAYS OF DEOSMANIZATION OF THE BALKANS (1912-1923) [PDF]

Historijski pogledi, 2020
The dramatic currents of the history of the 19th and 20th centuries in the Balkans cannot be seen in a more comprehensive way, separate from the wider European / world context, geopolitical order, influence and consequences of the interesting logics of ...
Safet Bandžović
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Luxury food tour: Perspectives and dilemmas on the "luxurification" of local culture in tourism product

Acta Geographica Slovenica, 2021
This paper focuses on the Kras/Carso Food Tour to present the challenges of developing a luxury tourism product. The tour's design followed the current strategy of the Slovenian Tourist Board, which defines specific criteria for a luxury experience ...
Saša Poljak Istenič, Jasna Fakin Bajec
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Politics and counter-politics of identity and space: Several cases from Belgrade’s streets in the 2000s [PDF]

Glasnik Etnografskog Instituta SANU, 2011
With the onset of political overturn in Serbia in 2000, the process of the ideological reconfiguration of public places was simultaneously being put in motion.
Radović Srđan
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Factors influencing music teaching among primary and early childhood education and care generalist teachers: a meta-narrative review

Frontiers in Education
A growing body of research has explored factors influencing music teaching among pre-service and in-service generalist teachers in primary and early childhood education and care (ECEC).
Thomas Nguyen, Thomas Nguyen, Jens Knigge, Morten Sæther, Lina Oravec   +4 more
doaj   +1 more source

Ribald Man with a cranky look. The Sarmatian portrait as the pop-cultural symbol of the Baroque in Poland [PDF]

Journal of Art Historiography, 2016
This article analyses how it was that the Sarmatian portrait, a phenomenon typical of Polish Baroque art in the twentieth century, came to be a symbol of Polishness, and to what extent this pop-cultural vision of the ‘Polish Baroque’ was formed by ...
Emilia Kłoda, Adam Szeląg
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source