Results 41 to 50 of about 239,653 (217)

PHILOSOPHICAL UNDERSTANDING OF THE ARCHETIPOLOGICAL BLOCK OF MEMORY IN COMPARATIVE ANALYSIS OF K.G. JUNG AND G. POPOV APPROACHES

open access: yesОсвітній дискурс, 2020
The current situation related to the necessity of elimination of the consequences of world pandemic and reorganization of the system of professional activity, as one leaves behind the “physical life” preferring it to the world of social networks ...
Oleg Maltsev
doaj   +1 more source

COVID-19 Impacts on Historic Soundscape Perception and Site Usage

open access: yesAcoustics, 2021
The ISO 12913 standards acknowledge the primacy of context in perceiving acoustic environments. In soundscape assessments, context is constituted by both physical surroundings and psychological, social, and cultural factors.
Pamela Jordan, André Fiebig
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Culture of Memory and Politics of History in Lithuania in 1989–2018

open access: yesReview (Institute of National Remembrance), 2019
This article aims to analyse the transformation of the culture of memory in Lithuania and the most important directions of Lithuanian politics of history in the period from 1989 to 2018.
Alvydas Nikžentaitis
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Women in the Socialist Fish-Canning Industry: Insights from the Yugoslav Adriatic Coast

open access: yesComparative Southeast European Studies
This article discusses the implications of including women in the labor force of the fish-canning factories on the Adriatic coast in socialist Yugoslavia.
Kosmos Iva, Petrović Tanja
doaj   +1 more source

Des lieux de memoire au cœur de la ville: les monuments aux morts dans l'est de la France (Alsace et Moselle) [PDF]

open access: yesIstorija 20. Veka, 2015
Između 1870 i 1945, Alzašani i deo Lorenaca12 (Mozelani13) menjali su svoju nacionalnost četiri puta. Za vreme dva svetska rata 1914–1918. i 1939–1945, neki su nosili francusku, a većina nemačku uniformu. Prvi svetski rat 1918.
Jean Noël Grandhomme
doaj  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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