Results 161 to 170 of about 2,309,175 (337)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Antibody-mediated SARS-CoV-2 entry in cultured cells. [PDF]

open access: yesEMBO Rep, 2023
Kibria MG   +16 more
europepmc   +1 more source

Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells [PDF]

open access: bronze, 2005
Dolores Garcia Arocena   +7 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

RC-IAL: linhagem celular contínua de rim de coelho - características e substrato para replicação de vírus

open access: yesRevista de Saúde Pública
Uma linhagem celular de rim de coelho (denominada RC-IAL), que foi isolada em 1976, e que atualmente está na 150ª passagem, teve suas características analisadas. As células apresentaram morfologia semelhante aos fibroblastos desde o início de seu cultivo.
Aurea Silveira Cruz   +4 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cardiac glycoside receptors in cultured heart cells II [PDF]

open access: yes, 1984
Brown, L.   +5 more
core   +2 more sources

In Vitro Exposure of Cultured Porcine Choroid Plexus Epithelial Cells to Immunosuppressant, Anti-Inflammatory, and Psychoactive Drugs

open access: green, 2007
Dwaine F. Emerich   +4 more
openalex   +2 more sources

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