Wnt3a signaling with serum supply induces replication stress in cultured cells. [PDF]
Wang Y+5 more
europepmc +1 more source
Indirect immunofluorescence tests with sera from African children and cultured Burkitt lymphoma cells [PDF]
Jean-Paul Lévy, Gertrude Henle
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Background: Retinal pigment epithelium (RPE) cells play an important role in the maintenance of normal function of the retina. Tyrosinase is a marker of RPE cells that functions in synthesis of melanin. Polymer of polyhydroxyethylmethacrylate (Poly-HEMA)
Fatemeh Nazem-Roaya+6 more
doaj
Cell surface profiling of cultured cells by direct hydrazide capture of oxidized glycoproteins. [PDF]
Tremblay TL+3 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Establishment of 9L/F344 rat intracerebral glioma model of brain tumor stem cells
Objective To establish the 9L/F344 rat intracerebral glioma model of brain tumor stem cells. Methods Rat 9L gliosarcoma stem-like cells were cultured in serum-free suspension. The expression of CD133 and nestin were tested by immunohistochemistry.
Zong-yu XIAO+2 more
doaj
Copper pyrithione and zinc pyrithione induce cytotoxicity and neurotoxicity in neuronal/astrocytic co-cultured cells via oxidative stress. [PDF]
Oh HN, Kim WK.
europepmc +1 more source
End Product Control of Amino Acid Synthesis by Cultured Human Cells
Harry Eagle+2 more
openalex +1 more source
Cytokinins From a Variant Strain of Cultured Soybean Cells [PDF]
George A. Miura, Carlos O. Miller
openalex +1 more source