Results 191 to 200 of about 2,309,175 (337)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Polymerization of recombinant tau core fragments in vitro and seeding studies in cultured cells. [PDF]

Front Neurosci, 2023
Paterno G, Bell BM, Riley-DiPaolo A, LaVoie MJ, Giasson BI.   +4 more
europepmc   +1 more source

Glibenclamide inhibits agonist-induced Ca2+ entry in cultured human aortic endothelial cells

, 1998
Miki Nakao, Kyoichi Ono, Hitomi Meguro, Toshihiko Iijima   +3 more
openalex   +1 more source

Propagation of Fast and Slow Intercellular Calcium Waves in Primary Cultured Smooth Muscle Cells [PDF]

, 2009
Nadia Halidi, Aurélie Formey, François-Xavier Boittin, Jean‐Louis Bény, Jean-Jacques Meister   +4 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Seeing the world through the eyes of cultured cells. [PDF]

Cell Metab
Tan J, Kunzmann GB, Virtue S, Cantor JR, Fazakerley DJ.   +4 more
europepmc   +1 more source

Myoglobin inhibits proliferation of cultured human proximal tubular (HK-2) cells

, 1996
Mineo Iwata, Richard A. Zager
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Protocol to assess changes in mitochondrial respiration in living cultured cells infected with flaviviruses. [PDF]

STAR Protoc
Barragan Torres VA, Chatel-Chaix L.
europepmc   +1 more source