Results 191 to 200 of about 12,036,045 (356)

Vitamin A and the biosynthesis of sulphated mucopolysaccharides. Experiments with rats and cultured neoplastic mast cells [PDF]

, 1969
D. B. Thomas, C. A. Pasternak
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells. [PDF]

Int J Mol Sci, 2023
Chiavetta RF, Titoli S, Barra V, Cancemi P, Melfi R, Di Leonardo A.   +5 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

Proceedings of the National Academy of Sciences of the United States of America, 2009
Kelvin C. Luk, Cheng Song, Patrick O’Brien, Anna M. Stieber, Jonathan R. Branch, K. Brunden, J. Trojanowski, V. Lee   +7 more
semanticscholar   +1 more source

Canine Distemper Virus cultured in a Diploid Monkey Cell Strain [PDF]

, 1964
Margaret J. Harrison
openalex   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Protocol for detection of cGAMP-induced STING oligomerization in cultured cells. [PDF]

STAR Protoc
Liu L, Manley JL.
europepmc   +1 more source

Distinct Effects of Chemical Toxicity and Radioactivity on Metabolic Heat of Cultured Cells Revealed by "Isotope-Editing". [PDF]

Microorganisms, 2023
Oertel J, Sachs S, Flemming K, Obeid MH, Fahmy K.   +4 more
europepmc   +1 more source

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium‐induced de‐ and hyperpolarization of neuronal mitochondria

Journal of Physiology, 2012
A. Gerencser, C. Chinopoulos, M. Birket, M. Jastroch, Cathy Vitelli, D. Nicholls, M. Brand   +6 more
semanticscholar   +1 more source