Results 281 to 290 of about 1,450,054 (334)
Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang +16 more
wiley +1 more source
Novel Phenotypes and Deep Intronic Variant Expand TH‐Associated Dopa‐Responsive Dystonia Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Approximately 20% of dopa‐responsive dystonia (DRD) cases remain genetically unresolved. Using whole‐genome sequencing, we identified two TH variants in a young DRD patient, including a novel deep intronic variant. Minigene assays confirmed that this variant causes aberrant splicing.
Xiaosheng Zheng +6 more
wiley +1 more source
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British Journal of Hospital Medicine, 2015
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Antonietta Messina, Loredana De Bartolo
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Antonietta Messina, Loredana De Bartolo
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The Culture of Cell Culture [PDF]
Science, 2007 Culturing Life . How Cells Became Technologies. By Hannah Landecker . Harvard University Press, Cambridge, MA, 2007. 288 pp. $35, £22.95, €32.30. ISBN 9780674023284. Landecker explores how culturing cells has changed our understanding of individuality, immortality, life, and ...
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Cell cultures and nephrolithiasis
World Journal of Urology, 1997While the physical chemistry of stone formation has been intensively studied during the last decade, it has become clear that the pathophysiology of renal stone disease cannot be explained by crystallization processes only. In recent years, evidence has emerged that the cells lining the renal tubules can have an active role in creating the conditions ...
Burt G. van der Boom +3 more
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2016
Cell culture is an important research method in virology. Although many attempts have been conducted to culture HEV in cells, only a few cell culture systems were considered to be efficient enough for usage. Concentration of virus stocks, host cells, and medium components affects the culture efficiency and the genetic mutations during HEV passage were ...
Feng Zhang, Youchun Wang
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Cell culture is an important research method in virology. Although many attempts have been conducted to culture HEV in cells, only a few cell culture systems were considered to be efficient enough for usage. Concentration of virus stocks, host cells, and medium components affects the culture efficiency and the genetic mutations during HEV passage were ...
Feng Zhang, Youchun Wang
openaire +4 more sources
, 1976 Many cell types can now be isolated and maintained in large quantities for long periods as a result of recent improvements in tissue culture techniques. Thus, it is possible to maintain normal and abnormal cells in vitro and under controlled conditions in order to study many questions of major importance in cell biology including cell differentiation ...
Ching Y. Shih, Richard G. Kessel
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Identification of cells in culture
American Journal of Hematology, 1976AbstractMost laboratories using cells cultured in vitro maintain multiple cell lines. Such lines should be monitored for species and intraspecies characteristics to prevent invalidation of research work due to incidents of cell line cross‐contamination.This report describes the results obtained when 246 cell cultures were examined for evidence of cross‐
C. S. Stulberg +2 more
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