Results 81 to 90 of about 56,372 (243)

Exploration of the In Vitro and In Vivo Neuroprotective Effects of Several Polyphenolics on LPS‐Induced Neuroinflammation

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Oxidative stress and neuroinflammation are key components in neurodegenerative diseases, where early intervention using natural treatments may offer neuroprotective effects. This study shows that isoliquiritigenin (ISL), hesperidin (HES), and curcumin (CUR) can mitigate lipopolysaccharide (LPS)‐induced neuroinflammation and oxidative stress in vitro ...
Mona Elkhatieb, Rasha A. Radwan, Doaa Abou El-ezz, Christine Adel Sedky, Ulrike Breitinger, Nabila Hamdi, Amira Emad Abdelaziz, Sarah Atef Fahim, Ahmed M. Hafez, Harleen Khatra   +9 more
wiley   +1 more source

The essential role of OhrR Cys21 in cumene hydroperoxide sensing in vivo.

, 2012
(A) Cultures of wild type (ATCC 12472) and ΔohrR mutant strains containing empty vector (pMR20) or the ΔohrR mutant strain complemented with OhrR, OhrR C7S, OhrR C21S, OhrR C126S and OhrR C143S were either untreated or treated with 200 µM cumene ...
Caroline C. Negretto (127448), José F. da Silva Neto (127444), Luis E. S. Netto (127450)   +2 more
core   +1 more source

Improving Net Energy of Cumene Hydroperoxide Production using Cumene Oxidation Process Through Removing Cooler on the Recycle System to Achieve Energy Efficiency and Reduce Production Cost

Journal of Chemical Engineering Research Progress
This study investigates a modification to the cumene hydroperoxide (CHP) production process by removing the cooler between the reactor and separator, aiming to improve energy efficiency.
Benaya Matius Marpaung, Henricus Jovan Setyanto, St Nur Aliyah, Lim Christoval Evandy Haryono   +3 more
doaj   +1 more source

Computational and Experimental Insights into a Ferric Cumylperoxido Species Stabilized in a Bispidine Scaffold

Zeitschrift für anorganische und allgemeine Chemie, Volume 651, Issue 18, December 10, 2025.
An iron(III)‐cumylperoxido intermediate has been generated that performs electrophilic and nucleophilic reactivity under ambient conditions. Iron‐containing alkylperoxido species are mostly unstable, although these are important reactive intermediates found in metalloenzymes.
Gunasekaran Velmurugan, Gourab Mukherjee, Umesh Kumar Bagha, Chivukula V. Sastri, Peter Comba   +4 more
wiley   +1 more source

Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450 [PDF]

, 1976
Highly purified liver microsomal cytochrome P-450 catalyzes the hydroperoxide-dependent hydroxylation of a variety of substrates in the absence of NADPH, NADPH-cytochrome P-450 reductase, and molecular oxygen.
White, Ronald E., Ronald E. White, Gerald D. Nordblom, Coon, Minor J., Minor J. Coon, Nordblom, Gerald D.   +5 more
core   +1 more source

Greater oxidative susceptibility of the surface monolayer in small dense LDL may contribute to differences in copper-induced oxidation among LDL density subfractions.

Journal of Lipid Research, 1995
We monitored peroxidative stress in the surface monolayer as compared with the outer core of large, buoyant (d 1.025-1.032 g/ml) and small, dense (d 1.040-1.054 g/ml) low density lipoprotein (LDL) subfractions using the oxidation-labile fluorescent ...
D L Tribble, R M Krauss, M G Lansberg, P M Thiel, J J van den Berg   +4 more
doaj   +1 more source

Oxidation of cumene by molecular oxygen on heterogenized cobalt catalysts

, 1986
In the oxidation of cumene to cumene hydroperoxide by molecular oxygen in the liquid phase, the cobalt(II) catalysts heterogenized on organic cation exchangers are active only if acid functional groups of the exchanger which bind cobalt ions show medium ...
Zdeněk Prokop, Karel Setínek, Stanislava Drapáková   +2 more
core   +1 more source

Synthesis of Oxy Aminated [60] and [70]Fullerenes with Cumene Hydroperoxide as Oxidant

, 2007
International audienceTreatment of [60] or [70]fullerene with excess secondary amine and 3 equiv. of cumene hydroperoxide regioselectively afforded a mono-oxygenated tetraamino or diamino fullerene in good to high yield.
Hiroyuki Isobe, Tanaka, Takatsugu, Nakamura, Eiichi, Loic Lemiegre, Takatsugu Tanaka, Lemiègre, Loïc, Nanao, Takeshi, Isobe, Hyroyuki, Eiichi Nakamura, Takeshi Nanao   +9 more
core   +1 more source

Evidence that intracellular cyclophilin A and cyclophilin A/CD147 receptor-mediated ERK1/2 signalling can protect neurons against in vitro oxidative and ischemic injury

Neurobiology of Disease, 2007
We previously reported that cyclophilin A protein is up-regulated in cortical neuronal cultures following several preconditioning treatments. In the present study, we have demonstrated that adenoviral-mediated over-expression of cyclophilin A in rat ...
Sherif Boulos, Bruno P. Meloni, Peter G. Arthur, Bernadette Majda, Christina Bojarski, Neville W. Knuckey   +5 more
doaj   +1 more source

Bifunctional Squaramide‐Catalyzed Oxidative Kinetic Resolution: Simultaneous Access to Axially Chiral Thioether and Sulfoxide

Advanced Science
Axially chiral thioethers and sulfoxides emerge as two pivotal classes of ligands and organocatalysts, which have remarkable features in the stereoinduction of various asymmetric transformations. However, the lack of easy methods to access such molecules
Wei Wen, Chang‐Lin Yang, Zhu‐Lian Wu, Dong‐Rong Xiao, Qi‐Xiang Guo   +4 more
doaj   +1 more source