Results 41 to 50 of about 194,005 (197)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Local CO2 Application within Strawberry Plant Canopy Increased Dry Matter Production and Fruit Yield in Summer and Autumn Culture

International Journal of Fruit Science, 2022
June-bearing strawberry cultivars have been widely grown in Japan. Since they are harvested in winter and spring, little produce is available in summer and autumn. To achieve stable year-round supply, we need to expand the production area of ever-bearing
Yuya Mochizuki, Sou Murakami, Takuro Kobayashi, Kanjana Worarad, Yukio Yonezu, Hiroki Umeda, Tsuyoshi Okayama, Eiichi Inoue   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Requirements for implementing a ‘just culture’ within healthcare organisations: an integrative review

BMJ Open Quality, 2023
Purpose To identify requirements for implementing a ‘just culture’ within healthcare organisations.Methods Using Whittemore and Knafl’s methodology for integrative reviews, we searched PubMed, PsychInfo, Cumulative Index of Nursing and Allied Health ...
Jonathan Lee, Donald Scott, John S Murray, Stacey Larson, Amy Range, Joan Clifford   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modeling effects of local extinctions on culture change and diversity in the paleolithic. [PDF]

PLoS ONE, 2010
The persistence of early stone tool technologies has puzzled archaeologists for decades. Cognitively based explanations, which presume either lack of ability to innovate or extreme conformism, do not account for the totality of the empirical patterns ...
L S Premo, Steven L Kuhn
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Basis for cumulative cultural evolution in chimpanzees: social learning of a more efficient tool-use technique. [PDF]

PLoS ONE, 2013
BACKGROUND: The evidence for culture in non-human animals has been growing incrementally over the past two decades. However, the ability for cumulative cultural evolution, with successive generations building on earlier achievements, in non-human animals
Shinya Yamamoto, Tatyana Humle, Masayuki Tanaka   +2 more
doaj   +1 more source

Rumen Fermentation and Microbiome Responses to Enzymatic Hydrolysate of Cottonseed Protein Supplementation in Continuous In Vitro Culture

Animals, 2022
This study aimed to evaluate the effect of enzymatic hydrolysate of cottonseed protein (ECP) on the kinetic of gas production, rumen fermentation characteristics, and microbial diversity in continuous in vitro culture with a single factorial design of ...
Jia Zhou, Ziyue Ding, Qijian Pu, Benchu Xue, Shuangming Yue, Shengtao Guan, Zhisheng Wang, Lizhi Wang, Quanhui Peng, Bai Xue   +9 more
doaj   +1 more source