Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
How to Reveal Magnitude of Gene Signals: Hierarchical Hypergeometric Complementary Cumulative Distribution Function. [PDF]
Evol Bioinform Online, 2018 Kim B.
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Detecting mammographically occult cancer in women with dense breasts using deep convolutional neural network and Radon Cumulative Distribution Transform. [PDF]
J Med Imaging (Bellingham), 2019 Lee J, Nishikawa RM.
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
The Radon Cumulative Distribution Transform and Its Application to Image Classification. [PDF]
IEEE Trans Image Process, 2016 Kolouri S, Park SR, Rohde GK.
europepmc +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Classification of images using Gaussian copula model in empirical cumulative distribution function space. [PDF]
PLoS OneIndratno SW, Winarni S, Sari KN.
europepmc +1 more source
Cumulative distribution function solutions of advection-reaction equations with uncertain parameters. [PDF]
Proc Math Phys Eng Sci, 2014 Boso F, Broyda SV, Tartakovsky DM.
europepmc +1 more source