Results 111 to 120 of about 1,180,431 (244)

Minimax Estimation of a Cumulative Distribution Function

The Annals of Statistics, 1973
In this paper the minimax estimators of a cumulative distribution function $F$ is obtained for four types of loss functions. The result is quite general in that no restrictions are imposed on the unknown $F$. Moreover, the estimates do not depend upon the weight function used in the definition of the loss functions.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Statistical Analysis of Annual DNI Distribution and its Impact on Bankability Assessment for Concentrated Solar Power Plants

SolarPACES Conference Proceedings
The Weibull distribution is commonly accepted as the most suitable model for describing the annual distribution of Direct Normal Irradiance (DNI). However, when the annual DNI is assumed to follow a Normal distribution instead of a Weibull distribution,
Miguel Larrañeta, Jose A López-Álvarez, Elena Pérez-Aparicio, Jose M. Delgado-Sanchez, Joaquín Alonso-Montesinos, Silva-Pérez Manuel A.   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Breakup of meteoroids in the Venusian atmosphere and its effects on crater formation [PDF]

Early results of the Magellan mission to Venus show that almost all of the observed impact craters appear to be unaffected by erosion, burial, and tectonic deformation.
Herrick, R. R., Phillips, Roger J.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Extension of the Misme and Fimbel model for the estimation of the cumulative distribution function of the differential rain attenuation between two converging terrestrial links

Journal of Microwaves, Optoelectronics and Electromagnetic Applications
A distribution-free model is presented for the cumulative distribution function of the differential rain attenuation between two co-channel converging terrestrial links operating at frequencies above 10 GHz.
Henrique Grynszpan, Emanoel Costa
doaj   +1 more source

Approximation of Cumulative Distribution Functions by Bernstein Phase-Type Distributions

Performance Evaluation
The inclusion of generally distributed random variables in stochastic models is often tackled by choosing a parametric family of distributions and applying fitting algorithms to find appropriate parameters. A recent paper proposed the approximation of probability density functions (PDFs) by Bernstein exponentials, which are obtained from Bernstein ...
András Horváth, Illés Horváth, Marco Paolieri, Miklós Telek, Enrico Vicario   +4 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Active distribution network feeder loop closing current assessment based on DK2-PLF

电力工程技术
The research of loop closing current assessment has great significance for distribution network feeder loop closing operation to supply power. In order to enhance the accuracy of active distribution network feeder loop closing current calculation, an ...
HUANG Yue, RONG Na, CHEN Shiwei, GUO Yuanping   +3 more
doaj   +1 more source