Results 81 to 90 of about 448,635 (294)

Competing risks analyses: objectives and approaches [PDF]

, 2017
Studies in cardiology often record the time to multiple disease events such as death, myocardial infarction, or hospitalization. Competing risks methods allow for the analysis of the time to the first observed event and the type of the first event.
Heinze, Georg, Jager, Kitty J., Koller, Michael T., Leffondré, Karen, Schaer, Beat, Stel, Vianda S., Wolbers, Marcel   +6 more
core  

Prophylactic use of carvedilol to prevent ventricular dysfunction in patients with cancer treated with doxorubicin [PDF]

, 2018
Objective: Deterioration in ventricular function is often observed in patients treated with anthracyclines for cancer. There is a paucity of evidence on interventions that might provide cardio-protection.
Abrar, Mohammed Burhan, Abuosa, Ahmed Mohamed, Ahmed, Adel H., Andejani, Abdulwahab, Cleland, John G.F., Elshiekh, Ayman Hassan, Kholeif, Mona A., Kinsara, Abdulhalim Jamal, Qureshi, Kahekashan   +8 more
core   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Prevalence and cumulative incidence of autism spectrum disorders and the patterns of co-occurring neurodevelopmental disorders in a total population sample of 5-year-old children

Molecular Autism, 2020
Backgrounds Whether there is a true increase in autism spectrum disorder (ASD) frequency or not remains unclear. Additionally, the rates of co-existing neurodevelopmental disorders (NDD) in a total population sample has not been fully examined before ...
Manabu Saito, Tomoya Hirota, Yui Sakamoto, Masaki Adachi, Michio Takahashi, Ayako Osato-Kaneda, Young Shin Kim, Bennett Leventhal, Amy Shui, Sumi Kato, Kazuhiko Nakamura   +10 more
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

Therapeutic Plasma Exchange Protects Patients with Sepsis-Associated Disseminated Intravascular Coagulation by Improving Endothelial Function

Clinical and Applied Thrombosis/Hemostasis, 2021
The mortality rate of sepsis-associated disseminated intravascular coagulation (DIC) is high. This study aimed to explore the efficacy of therapeutic plasma exchange (TPE) in sepsis-associated DIC patients by improving endothelial function.
Junting Weng MD, Min Chen MD, Dexiang Fang MD, Danjuan Liu PhD, Rongjie Guo MD, Shuzhen Yang MD   +5 more
doaj   +1 more source

Brief Report: A Multidisciplinary Initial Workup for Suspected Lung Cancer as Fast-Track Intervention to Histopathologic Diagnosis

JTO Clinical and Research Reports, 2023
Guidelines for optimal timing of lung cancer diagnosis and treatment have been implemented in many countries, but the effect of fast-track interventions on the shortening of time interval is still debatable.
Jean-Louis Pujol, MD, PhD, Grégoire Mercier, MD, PhD, Maria Vasile, MCS, Isabelle Serre, MD, PhD, Hélène Vernhet-Kovacsik, MD, PhD, Sébastien Bommart, MD, PhD   +5 more
doaj   +1 more source

On null hypotheses in survival analysis

, 2019
The conventional nonparametric tests in survival analysis, such as the log-rank test, assess the null hypothesis that the hazards are equal at all times. However, hazards are hard to interpret causally, and other null hypotheses are more relevant in many
Ryalen, Pål Christie, Røysland, Kjetil, Stensrud, Mats Julius   +2 more
core   +1 more source

The two-stage clonal expansion model in occupational cancer epidemiology: Results from three cohort studies [PDF]

, 2010
Copyright © 2010 by the BMJ Publishing Group Ltd. All rights reserved.Objectives: The objective of this work was to apply the two-stage clonal expansion model, with the intention to expand the literature on epidemiological applications of the model and ...
Gore, R, Kriebel, D, Zeka, A
core   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source