Results 221 to 230 of about 228,576 (271)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

open access: yesAdvanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin   +6 more
wiley   +1 more source

Evolution of cumulative live birth, cumulative multiple live birth and drop-out rates over six complete IVF/ICSI cycles: a large prospective cohort study

open access: yes, 2021
De Neubourg, Diane   +9 more
openaire   +1 more source

Growing up in Scotland : the involvement of grandparents in children’s lives [PDF]

open access: yes, 2012
Bradshaw, Paul   +2 more
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Does PGT-A affect cumulative live birth rate?

Current Opinion in Obstetrics & Gynecology, 2023
Purpose of review Preimplantation genetic testing for the purpose of aneuploidy screening (PGT-A) has increased in use over the last decade. Recent findings Whether PGT-A benefits all of the patients that choose to employ it has been a concern, as recent
S. Seckin, E. Forman
semanticscholar   +3 more sources

Total Blastocyst Usable Rate is a predictor of cumulative live birth rate in IVF cycles.

Journal of Gynecology Obstetrics and Human Reproduction
Despite advances in IVF techniques, determining the prognostic factors influencing cumulative live birth rate (CLBR) remains crucial for optimizing outcomes. Among the various key performance indicators in the lab, blastulation rate, and more specifically Total Blastocyst Usable Rate (TBUR), has gained particular interest.
M. Chaillot, A. Reignier, T. Fréour
semanticscholar   +5 more sources

Association Between Number of Oocytes Retrieved with Cumulative Live Birth Rate

Fertility Science and Research
To find the correlation between oocyte number and cumulative live birth rate (CLBR) in different age groups. It is a retrospective cohort study conducted from January 2022 to December 2022 at Centre of IVF & Human Reproduction, Sir Gangaram Hospital ...
Deepika Nagarwal   +3 more
semanticscholar   +2 more sources

Cumulative live birth rates in in-vitro fertilization

Minerva Ginecologica, 2019
Traditionally, in-vitro fertilization (IVF) success rates have been reported in terms of live birth per fresh cycle or embryo transfer. However, reporting IVF outcomes using cumulative live birth rates (LBR), defined as the first live birth following the use of all fresh and frozen embryos derived from a single ovarian stimulation cycle appears to be a
Drakopoulos, Panagiotis   +7 more
openaire   +5 more sources

Estradiol on trigger day: Irrelevant to live birth rates of fresh cycles but positively associated with cumulative live birth rates

International Journal of Gynecology & Obstetrics, 2023
AbstractObjectiveTo assess the effects of estradiol (E2) on trigger day on cumulative live birth rates (CLBRs), and pregnancy outcomes after fresh and frozen–thawed embryo transfer (FET).MethodsThis multicenter retrospective cohort study included 42 315 patients from five reproductive centers. Six subgroups were divided according to E2 on trigger day (&
Meng Wang   +6 more
openaire   +2 more sources

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