Results 121 to 130 of about 92,261,605 (285)

Mengukur Tingkat Keparahan Cup-To-Disc-Ratio Glaucoma Fundus Menggunakan Metode Ellipse Fitting

open access: yes, 2020
Based on the data and information center of the Indonesian Ministry of Health in 2019, glaucoma is the second largest cause of blindness after cataracts.
Nasution, Najmiyah Bey
core  

Long-term fluctuations of the normalised rim/disc area ratio quotient in normal eyes

open access: yes, 1999
The assessment of the cup of the optic disc in follow-up of glaucomatous optic nerve heads depends on the variability of the cup area over time. We examined the variability of topographic measurements depending on scan focus settings and evaluated the ...
Bartz-Schmidt, K U   +5 more
core   +1 more source

Programmable Sequential 4D Actuation in Multistable Kirigami Metamaterials

open access: yesAdvanced Science, EarlyView.
This study presents a modular kirigami metamaterial framework enabling programmable multistability and sequential 4D actuation. By coupling geometry‐controlled multistability with material‐dependent recovery kinetics, spatiotemporal deformation can be precisely programmed.
Eui‐Hyun Kim   +3 more
wiley   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

open access: yesAdvanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian   +12 more
wiley   +1 more source

SwinCup-DiscNet: A fusion transformer framework for glaucoma diagnosis using optic disc and cup features

open access: yesScientific Reports
Glaucoma remains a critical cause of permanent global visual disability, and is produced by advancing destruction of the visual nerve head (ONH). Early detection is critical important in preventing vision loss.
Rajitha Chilukuri   +3 more
doaj   +1 more source

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

open access: yesAdvanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang   +16 more
wiley   +1 more source

Intraocular pressure and optic disc cupping in school-aged children: An epidemiological study in Taiwan

open access: yesTaiwan Journal of Ophthalmology
PURPOSE: The purpose of the study was to investigate intraocular pressure (IOP), cup-to-disc ratio (CDR), and ocular biometrics in school-aged children in Taiwan and to evaluate the factors associated with IOP and CDR.
Hsiao-Lien Chang   +10 more
doaj   +1 more source

Retinal Vessel Density in Subjects with Asymmetric Cup-to-Disc Ratio

open access: yes, 2019
Asymmetric cup-to-disc ratio (CDR) has been known as one of features of possible glaucoma. Optical coherence tomography angiography (OCT-A) enables non-invasively detect retinal microvasculature network.
Pai-Huei Peng; Hui-Chen Lin
core  

Home - About - Disclaimer - Privacy