Results 101 to 110 of about 1,666,845 (324)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Inventer des « dispositifs génératifs » à la croisée de l’ethnographie et du design
Ateliers d'AnthropologieIn the form of a dialogue, this article looks back at a collaboration between ethnography and design. As part of an ongoing study on the practices of the Vieux Marché in Brussels, Virginie Milliot and Léna organised the “Histoires de Brol” festival. They
Virginie Milliot, Léna Paté
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Bulletin of the History of Archaeology, 1993 The origin of humans, whether at the "point" of divergence from other primates, from other hominid species, or within the last several hundred thousand years, are very active and contested areas of paleoanthropological research ...
Marc Kodack
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M/C Journal, 2015 We live in the “age of curation”, according to Eliot van Buskirk. In this issue of M/C Journal we bring together authors from diverse fields to explore what this ‘age’ looks, sounds and feels like. In so doing, the papers highlight both the ubiquitous and contested nature of curation.
Cathy Hope, Bethaney Turner
openaire +1 more source
Use of computer forensics in the digital curation of removable media [PDF]
, 2009 The purpose of this paper is to encourage the discussion of the potential place and value of digital forensics techniques when dealing with acquisitions on removable media in the field of digital curation.
Glisson, W.B.
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Beilstein Journal of Nanotechnology, 2015 The Nanomaterial Data Curation Initiative (NDCI), a project of the National Cancer Informatics Program Nanotechnology Working Group (NCIP NanoWG), explores the critical aspect of data curation within the development of informatics approaches to ...
Christine Ogilvie Hendren +3 more
doaj +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source