Results 111 to 120 of about 1,710,954 (275)

Curate

M/C Journal, 2015
We live in the “age of curation”, according to Eliot van Buskirk. In this issue of M/C Journal we bring together authors from diverse fields to explore what this ‘age’ looks, sounds and feels like. In so doing, the papers highlight both the ubiquitous and contested nature of curation.
Cathy Hope, Bethaney Turner
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Origin of Modern Humans and the Impact of Chronometric Dating, edited by M.J. Aitken, C.B. Stringer, and P.A. Mellars. Princeton University Press, Princeton, 1993

Bulletin of the History of Archaeology, 1993
The origin of humans, whether at the "point" of divergence from other primates, from other hominid species, or within the last several hundred thousand years, are very active and contested areas of paleoanthropological research ...
Marc Kodack
doaj   +1 more source

Digital curation and the cloud [PDF]

, 2012
Digital curation involves a wide range of activities, many of which could benefit from cloud deployment to a greater or lesser extent. These range from infrequent, resource-intensive tasks which benefit from the ability to rapidly provision resources
Aitken, B., McCann, P., McHugh, A., Miller, K.   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Nanomaterial Data Curation Initiative: A collaborative approach to assessing, evaluating, and advancing the state of the field

Beilstein Journal of Nanotechnology, 2015
The Nanomaterial Data Curation Initiative (NDCI), a project of the National Cancer Informatics Program Nanotechnology Working Group (NCIP NanoWG), explores the critical aspect of data curation within the development of informatics approaches to ...
Christine Ogilvie Hendren, Christina M. Powers, Mark D. Hoover, Stacey L. Harper   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

“Now Is the Time to Include the Films Produced by the Alexandru Sahia Documentary Studio in Our Conversations About the Communist Past.” An Interview with Adina Brãdeanu

Martor, 2019
An interview with researcher Adina Brădeanu (University of Oxford) around the topic of curating film heritage. Since 2014, Brădeanu has curated a DVD series (SAHIA VINTAGE) which rediscovers the output and the production culture of the Alexandru Sahia ...
Ionuț Mareș
doaj  

Curating E-Mails; A life-cycle approach to the management and preservation of e-mail messages [PDF]

, 2006
E-mail forms the backbone of communications in many modern institutions and organisations and is a valuable type of organisational, cultural, and historical record.
Pennock, Mrs Maureen
core