Results 231 to 240 of about 1,710,954 (275)
Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study
Arthritis Care &Research, EarlyView.Objective
This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods
This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel +19 morewiley +1 more sourceExploring the strengths and limitations of AI-driven variant prioritization versus manual curation in inborn errors of immunity. [PDF]
Front GenetMoushib LI, Moreno-Ruiz N, Martín-Nalda A, Rivière JG, Urban B, Dieli-Crimi R, Perurena-Prieto J, Aguiló-Cucurull A, Pérez-Estévez E, Solanich X, Soler-Palacín P, Colobran R, Batlle-Masó L. +12 moreeuropepmc +1 more sourceA Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development
Arthritis Care &Research, EarlyView.Objective
A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son +20 morewiley +1 more sourceThree-Year Long-Term Outcomes in Patients With Unresectable Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab Treatment in Clinical Practice. [PDF]
Cancer MedOhama H, Hiraoka A, Tada T, Hirooka M, Kariyama K, Tani J, Atsukawa M, Takaguchi K, Itobayashi E, Fukunishi S, Tsuji K, Ishikawa T, Tajiri K, Tanaka H, Toyoda H, Ogawa C, Nishimura T, Hatanaka T, Kakizaki S, Kawata K, Naganuma A, Kosaka H, Matono T, Kuroda H, Yata Y, Nishikawa H, Imai M, Aoki T, Ochi H, Tamai H, Komatsu S, Tada F, Nakamura S, Nakamura Y, Miyake T, Yoshida O, Nouso K, Morishita A, Itokawa N, Okubo T, Arai T, Tsutsui A, Nagano T, Tanaka K, Matsuura T, Koshiyama Y, Kanayama Y, Noritake H, Enomoto H, Matsui K, Kaibori M, Fukumoto T, Hiasa Y, Kudo M, Kumada T, RELPEC Group and HCC 48 Group. +55 moreeuropepmc +1 more sourceResponse to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout
Arthritis Care &Research, EarlyView.Objective
Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin +13 morewiley +1 more sourcePredictive factors for severity and poor treatment response in children with Evans syndrome: A retrospective cohort study. [PDF]
Front ImmunolBen Khaled M, Ben Ayed M, Zaroui Z, Ben Fraj I, Rekaya S, Mekki N, Chebbi Y, Ben Taieb A, Merdassi A, Zaiter I, Lamouchi T, Kouki R, Kaabi H, Slama H, Achour W, Bejaoui M, Mellouli F, Ben-Mustapha I, Ouederni M. +18 moreeuropepmc +1 more sourceNutritional practices and impact of feeding adequacy on clinical outcomes in Chinese respiratory intensive care units patients: a prospective observational study (ORIENT study). [PDF]
Front NutrHuang X, Wang Y, Geng S, Liang Y, Gao F, Wang T, Zhang H, Fang J, Wang C, Gu X, Yang J, Cheng Z, Liu C, Lei W, Hu X, Luo H, Fan H, Zhang Y, Li G, Di Q, Xing L, Li Y, Tong J, Chen L, Sun W, Chen L, Wang S, Li S, Liu J, Qin H, Qiu X, Ma Z, Li Y, Zhao H, Liang R, Wang L, Gao P, Sang L, Li D, Hou P, Zhang X, Wang D, Zheng L, Hua F, Jiang J, Li X, Nie Q, Zhao H, Huang C, Ji Y, Yu H, Song L, Jin J, Li N, Qian W, Zeng J, Chen L, Sun J, He W, Guan S, Chai S, Hu S, Li G, Li J, Jiang H, Zhong X, Li J, Zhao J, Du W, Zhang J, Liu Z, van Zanten A, Tian Y, Cai Y, Zhan Q. +74 moreeuropepmc +1 more source
