Results 61 to 70 of about 19,754 (217)

Red Shoes

The International Journal of Screendance, 2019
My mother watched the musicals that came on television in the middle of the day in Australia in the 1970s. So we did too. She knew all the songs and sang along.
Erin Brannigan
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

The Kitchen Sink Too

British Art Studies, 2019
“The Kitchen Sink Too: British Art 1945–1975” is a project led by Research Curator, Abi Shapiro at Museums Sheffield. The project undertakes research into Sheffield’s post-war visual art holdings to improve public access to the collection through a range
Abi Shapiro
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Miscellaneous earthworm types in the Natural History Museum, London (Annelida: Oligochaet a: Megadrilacea: Eudrilidae, Lumbricidae, Megascolecidae, Moniligastridae, Octochaetidae) [PDF]

Opuscula Zoologica Instituti Zoosystematici et Oecologici Universitatis Budapestinensis, 2014
Recently restored Lumbricus terrestris Linnaeus, 1758 neotype (NHM Register No. 1973.1.1) is described in greater detail. A lectotype is designated for Amynthas morrisi (Beddard, 1892) and an informal A. morrisi clonal speciescomplex is proposed.
Robert J. Blakemore
doaj  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Harmonizing data on correlates of sleep in children within and across neurodevelopmental disorders: lessons learned from an Ontario Brain Institute cross-program collaboration

Frontiers in Neuroinformatics
There is an increasing desire to study neurodevelopmental disorders (NDDs) together to understand commonalities to develop generic health promotion strategies and improve clinical treatment.
Patrick G. McPhee, Patrick G. McPhee, Patrick G. McPhee, Patrick G. McPhee, Anthony L. Vaccarino, Sibel Naska, Kirk Nylen, Jose Arturo Santisteban, Jose Arturo Santisteban, Rachel Chepesiuk, Andrea Andrade, Stelios Georgiades, Stelios Georgiades, Brendan Behan, Alana Iaboni, Flora Wan, Sabrina Aimola, Heena Cheema, Jan Willem Gorter, Jan Willem Gorter, Jan Willem Gorter, Jan Willem Gorter   +21 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Leveraging exceptions and limitations for digital curation and online collections

Libellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2017
Librarians wanting to use digital affordances for their patron’s and public benefit have increasingly found themselves frustrated by copyright law designed for a pre-digital era.
Patricia Aufderheide
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source