Results 41 to 50 of about 1,360,045 (268)
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Investigating Curatorial Voice with Corpus Linguistic Techniques
Museum & Society, 2020 We seek to demonstrate how corpus linguistic techniques can facilitate a comprehensive account of curatorial voice in a large digitised museum catalogue and hence leverage its value as a resource for generating new knowledge about: curatorial practice ...
Andrew Salway, James Baker
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Leveraging exceptions and limitations for digital curation and online collections
Libellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2017 Librarians wanting to use digital affordances for their patron’s and public benefit have increasingly found themselves frustrated by copyright law designed for a pre-digital era.
Patricia Aufderheide
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The International Journal of Screendance, 2019 My mother watched the musicals that came on television in the middle of the day in Australia in the 1970s. So we did too. She knew all the songs and sang along.
Erin Brannigan
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
British Art Studies, 2019 “The Kitchen Sink Too: British Art 1945–1975” is a project led by Research Curator, Abi Shapiro at Museums Sheffield. The project undertakes research into Sheffield’s post-war visual art holdings to improve public access to the collection through a range
Abi Shapiro
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