Results 21 to 30 of about 1,363,609 (268)

Connecting Data Publication to the Research Workflow: A Preliminary Analysis

open access: yesInternational Journal of Digital Curation, 2017
The data curation community has long encouraged researchers to document collected research data during active stages of the research workflow, to provide robust metadata earlier, and support research data publication and preservation.
Sünje Dallmeier-Tiessen   +5 more
doaj   +1 more source

The Digital Curation Centre: A Vision for Digital Curation [PDF]

open access: yes2005 IEEE International Symposium on Mass Storage Systems and Technology, 2006
We describe the aims and aspirations for the Digital Curation Centre (DCC), the UK response to the realisation that digital information is both essential and fragile. We recognise the equivalence of preservation as "interoperability with the future", asserting that digital curation is concerned with "communication across time". We see the DCC as having
Rusbridge, C.   +6 more
openaire   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

The Copyrights Chain in the Digital Curation Process

open access: yesInternational Journal of Digital Curation
The internet era, open access movement, image sharing platforms, and mainly the rise of artificial intelligence (AI) emphasise the importance of providing moderated access and licences for the reuse of collections by memory institutes as a key step in ...
Keren Barner
doaj   +1 more source

The Origin of Modern Humans and the Impact of Chronometric Dating, edited by M.J. Aitken, C.B. Stringer, and P.A. Mellars. Princeton University Press, Princeton, 1993

open access: yesBulletin of the History of Archaeology, 1993
The origin of humans, whether at the "point" of divergence from other primates, from other hominid species, or within the last several hundred thousand years, are very active and contested areas of paleoanthropological research ...
Marc Kodack
doaj   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior   +11 more
wiley   +1 more source

Out of Our Heads! Four perspectives on the curation of an on-line exhibition of medically themed artwork by UK medical undergraduates [PDF]

open access: yesMedical Education Online, 2010
The Medical School at Bristol University is noted for offering, and in some instances requiring, its students to work creatively with medical themes. Students, artists, educationalists and a web designer have worked to create an on-line exhibition of the
Trevor Thompson   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Endosomal H2O2 Molecules Act as Signaling Mediators in Akt/PKB Activation

open access: yesAntioxidants
Receptor-mediated endocytosis (RME) is a commonly recognized receptor internalization process of receptor degradation or recycling. However, recent studies have supported that RME is closely related to signal propagation and amplification from the plasma
Sujin Park   +3 more
doaj   +1 more source

Scientific Data Management in the Age of Big Data: An Approach Supporting a Resilience Index Development Effort

open access: yesFrontiers in Environmental Science, 2019
The increased availability of publicly available data is, in many ways, changing our approach to conducting research. Not only are cloud-based information resources providing supplementary data to bolster traditional scientific activities (e.g., field ...
Linda C. Harwell   +3 more
doaj   +1 more source

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